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Equity Incentive Plans
 3 Months Ended
Mar. 31, 2022
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Equity Incentive Plans

10.  Equity Incentive Plans

2013 Equity Incentive Plan

A total of 9,600,000 shares of common stock have been reserved for issuance under the La Jolla Pharmaceutical Company 2013 Equity Incentive Plan (the “2013 Equity Plan”). As of March 31, 2022 and December 31, 2021, 3,167,189 and 5,503,796 shares of common stock, respectively, remained available for future grants under the 2013 Equity Plan.

2018 Employee Stock Purchase Plan

A total of 750,000 shares of common stock have been reserved for issuance under the La Jolla Pharmaceutical Company 2018 Employee Stock Purchase Plan (the “ESPP”). As of March 31, 2022 and December 31, 2021, 293,412 and 335,473 shares of common stock, respectively, remained available for future grants under the ESPP.

Equity Awards

The activity related to equity awards, which are comprised of stock options, during the three months ended March 31, 2022 is summarized as follows:

 

 

Equity

Awards

 

 

Weighted-

average

Exercise Price

per Share

 

 

Weighted-

average

Remaining

Contractual

Term(1)

(years)

 

 

Aggregate

Intrinsic

Value(2)

(millions)

 

Outstanding at December 31, 2021

 

 

4,096,204

 

 

$

7.22

 

 

 

 

 

 

 

 

 

Granted

 

 

2,427,605

 

 

$

4.78

 

 

 

 

 

 

 

 

 

Exercised

 

 

-

 

 

$

-

 

 

 

 

 

 

 

 

 

Cancelled/forfeited

 

 

(90,998

)

 

$

5.86

 

 

 

 

 

 

 

 

 

Outstanding at March 31, 2022

 

 

6,432,811

 

 

$

6.32

 

 

 

8.6

 

 

$

0.3

 

Exercisable at March 31, 2022

 

 

1,940,093

 

 

$

10.13

 

 

 

6.9

 

 

$

0.1

 

(1) Represents the weighted-average remaining contractual term of stock options.

(2) Aggregate intrinsic value represents the product of the number of equity awards outstanding or equity awards exercisable multiplied by the difference between the Company’s closing stock price per share on the last trading day of the period, which was $4.27 as of March 31, 2022, and the exercise price.

 

 

Share-based Compensation Expense

The classification of share-based compensation expense is summarized as follows (in thousands):

 

 

 

Three Months Ended

 

 

 

March 31,

 

 

 

2022

 

 

2021

 

Selling, general and administrative

 

$

1,245

 

 

$

840

 

Research and development

 

 

17

 

 

 

276

 

Total share-based compensation expense

 

$

1,262

 

 

$

1,116

 

 

As of March 31, 2022, total unrecognized share-based compensation expense related to unvested equity awards was $14.2 million, which is expected to be recognized over a weighted-average period of 3.2 years. As of March 31, 2022, there was no unrecognized share-based compensation expense related to shares of common stock issued under the ESPP.