Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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Business - Additional Information (Details) - USD ($) $ in Thousands	Jan. 12, 2021	Jul. 28, 2020	Dec. 31, 2021	Dec. 31, 2020
Business Acquisition [Line Items]
Cash and cash equivalents			$ 46,668	$ 21,221
License Agreement Terms
Business Acquisition [Line Items]
Proceeds from upfront cash payment	$ 22,500
Percentage of refundable tax withholding	15.00%
Commercial milestone payments	$ 109,500
Tetraphase Pharmaceuticals, Inc.
Business Acquisition [Line Items]
Upfront cash for acquisition		$ 42,990
Future cash payments		$ 16,000