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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Operating activities        
Net income (loss) $ (2,260) $ (11,760) $ 15,891 $ (35,943)
Adjustments to reconcile net income (loss) to net cash provided by (used for) operating activities:        
Share-based compensation expense     3,315 5,385
Depreciation expense     84 2,155
Non-cash interest expense     5,587 5,339
Inventory fair value step-up adjustment included in cost of product sales     850 1,186
Amortization of intangible assets 400 300 1,164 259
Loss on change in fair value of contingent value rights     395  
Amortization of right-of-use lease assets     169 1,091
Loss on short-term investments       502
Loss on disposal of property and equipment, net of gain on lease termination       59
Changes in operating assets and liabilities:        
Accounts receivable, net     (2,959) 218
Inventory, net     (931) (1,482)
Prepaid expenses and other current assets     (875) 2,445
Accounts payable     (448) (1,649)
Accrued expenses     4,083 (5,786)
Accrued payroll and related expenses     (1,077) (2,168)
Lease liabilities     (168) (1,969)
Net cash provided by (used for) operating activities     25,080 (30,358)
Investing activities        
Acquisition of Tetraphase, net of cash, cash equivalents and restricted cash acquired       (33,513)
Proceeds from the sale of property and equipment       3,070
Purchases of property and equipment     (9)  
Proceeds from the sale of short-term investments       2,497
Purchases of short-term investments       (2,999)
Net cash used for investing activities     (9) (30,945)
Financing activities        
Net proceeds from issuance of common stock under ESPP     317 428
Net proceeds from issuance of common stock under 2013 Equity Plan     156 605
Net cash provided by financing activities     473 1,033
Net increase (decrease) in cash, cash equivalents and restricted cash     25,544 (60,270)
Cash, cash equivalents and restricted cash, beginning of period     21,261 88,729
Cash, cash equivalents and restricted cash, end of period 46,805 28,459 46,805 28,459
Reconciliation of cash, cash equivalents and restricted cash to the condensed consolidated balance sheets        
Cash and cash equivalents 46,765 27,760 46,765 27,760
Restricted cash 40 699 40 699
Cash, cash equivalents and restricted cash, end of period $ 46,805 $ 28,459 $ 46,805 $ 28,459