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License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended
Jan. 12, 2021
Mar. 31, 2021
Mar. 31, 2019
Mar. 31, 2021
Mar. 31, 2020
George Washington          
Research And Development Arrangement Contract To Perform For Others [Line Items]          
Milestone payment         $ 500,000
Percentage of royalty on net sales       6.00%  
Percentage of payments received from sublicensee       15.00%  
Royalty payments       $ 2,800,000 $ 400,000
Harvard          
Research And Development Arrangement Contract To Perform For Others [Line Items]          
Percentage of royalty on net sales       5.00%  
Percentage of payments received from sublicensee       20.00%  
Clinical development and regulatory milestones amount payable       $ 15,100,000  
Percentage of minimum royalty rate       4.50%  
Percentage of maximum royalty based on achievement of annual net product sales thresholds       7.50%  
Royalties payment       $ 100,000  
Payments related to clinical development and regulatory milestones       0  
Paratek          
Research And Development Arrangement Contract To Perform For Others [Line Items]          
Percentage of royalty on net sales     2.25%    
Royalties payment       $ 51,000  
Claim expiration       2023-10  
PAION AG          
Research And Development Arrangement Contract To Perform For Others [Line Items]          
Milestone payment $ 109,500,000        
Upfront cash payment $ 22,500,000        
Percentage of refundable tax withholding 15.00%        
Everest Medicines Limited          
Research And Development Arrangement Contract To Perform For Others [Line Items]          
Additional regulatory milestone payments receivable   $ 8,000,000.0   $ 8,000,000.0  
Sales milestone payments receivable   20,000,000.0   $ 20,000,000.0  
Royalties payable description       Royalties are payable with respect to each jurisdiction in the Everest Territory until the latest to occur of: (1) the last-to-expire of specified patent rights in such jurisdiction in the Everest Territory; (2) expiration of marketing or regulatory exclusivity in such jurisdiction in the Everest Territory; or (3) 10 years after the first commercial sale of a product in such jurisdiction in the Everest Territory.  
Royalties payable period after first commercial sale of product       10 years  
Milestone payments received   $ 3,000,000.0   $ 3,000,000.0