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Balance Sheet Details - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Apr. 22, 2020
Dec. 31, 2019
Restricted Cash And Cash Equivalents Items [Line Items]      
Restricted cash $ 40,000   $ 909,000
Inventory, net 6,013,000   2,211,000
Inventory reserves 900,000   100,000
Proceeds from disposal of tenant improvements and certain equipment 3,070,000    
Promissory Note | Paycheck Protection Program (PPP Loan)      
Restricted Cash And Cash Equivalents Items [Line Items]      
Promissory note   $ 2,300,000  
Debt instrument, interest rate   1.00%  
Tetraphase Pharmaceuticals, Inc. | Fair Value Step-Up Adjustment to Inventory      
Restricted Cash And Cash Equivalents Items [Line Items]      
Inventory, net 900,000    
San Diego Lease      
Restricted Cash And Cash Equivalents Items [Line Items]      
Loss on termination of lease 13,000,000.0    
Proceeds from disposal of tenant improvements and certain equipment 3,100,000    
Credit Card      
Restricted Cash And Cash Equivalents Items [Line Items]      
Restricted cash $ 40,000    
Standby Letters of Credit | San Diego Lease      
Restricted Cash And Cash Equivalents Items [Line Items]      
Restricted cash     $ 900,000