Commitments and Contingencies - Additional Information (Details)		1 Months Ended			2 Months Ended	3 Months Ended		9 Months Ended
	Dec. 29, 2016 USD ($)	Sep. 30, 2020 USD ($)	Jan. 31, 2020 ft²	Nov. 30, 2018	Sep. 30, 2020 USD ($)	Sep. 30, 2020 USD ($)	Sep. 30, 2019 USD ($)	Sep. 30, 2020 USD ($)	Sep. 30, 2019 USD ($)	Jul. 28, 2020 USD ($)	Feb. 01, 2020 ft²	Dec. 31, 2019 USD ($) ft²	Oct. 30, 2019 USD ($)
Lessee Lease Description [Line Items]
Restricted cash		$ 699,000			$ 699,000	$ 699,000		$ 699,000				$ 909,000
Right-of-use lease assets		2,150,000			2,150,000	2,150,000		2,150,000				$ 15,491,000
Tetraphase Pharmaceuticals, Inc.
Lessee Lease Description [Line Items]
Restricted cash		200,000			200,000	200,000		200,000
Standby Letters of Credit | Tetraphase Pharmaceuticals, Inc.
Lessee Lease Description [Line Items]
Security deposit		200,000			200,000	200,000		$ 200,000
San Diego Lease
Lessee Lease Description [Line Items]
Term of lease contract	10 years
Renewal term of lease contract	5 years
Lessee, Operating Lease, Existence of Option to Extend [true false]	true
Operating ease option to extend								The Company had an option to extend the San Diego Lease for an additional 5 years at the end of the Initial Lease Term
Lessee, Operating Lease, Existence of Option to Terminate [true false]								true
Lessee, option to terminate, description								On August 6, 2020, La Jolla received notice from the Landlord that the Landlord exercised its option to terminate the San Diego Lease effective August 31, 2020.
Loss on termination of lease		12,900,000
Restricted cash		0			0	0		$ 0
Right-of-use lease assets		0			0	0		0
Operating lease, liability		0			0	0		0
Lease expense						500,000	$ 700,000	$ 1,800,000	$ 2,100,000
San Diego Lease | Standby Letters of Credit
Lessee Lease Description [Line Items]
Security deposit	$ 900,000												$ 600,000
Tetraphase Agreement with Watertown Lease
Lessee Lease Description [Line Items]
Lessee, Operating Lease, Existence of Option to Extend [true false]				true
Operating ease option to extend								. In November 2018, Tetraphase entered into an Eighth Amendment to the Watertown Lease to extend the term of the lease through November 30, 2022 (the “Lease Term”).
Premises space leased | ft²											21,539	37,438
Decrease in space of premises lease | ft²			15,899
Aggregate remaining payments under lease										$ 2,600
Watertown Lease
Lessee Lease Description [Line Items]
Operating lease, liability		2,234,000			2,234,000	2,234,000		$ 2,234,000
Lease expense					200,000
Aggregate remaining payments under lease		$ 2,446,000			$ 2,446,000	$ 2,446,000		$ 2,446,000