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Organization and Summary of Significant Accounting Policies (Details Textual) (USD $)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 0 Months Ended
May 31, 2010
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Dec. 31, 2012
Segment
Dec. 31, 2011
Feb. 29, 2012
Feb. 17, 2012
Jan. 19, 2012
Apr. 14, 2011
Dec. 31, 2010
May 26, 2010
Dec. 31, 2012
Maximum [Member]
Dec. 31, 2012
Minimum [Member]
Mar. 31, 2011
Series E Convertible Preferred Stock [Member]
Dec. 31, 2012
Series C-2 Convertible Preferred Stock [Member]
Sep. 24, 2013
Private Placement [Member]
Sep. 24, 2013
Private Placement [Member]
Common Stock [Member]
Sep. 24, 2013
Private Placement [Member]
Series F Convertible Preferred Stock [Member]
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]                                        
Securities Purchase Agreement, Consideration Received Per Transaction                                     $ 10,000,000  
Securities Purchase Agreement, Number Of Shares Issued In Transaction                                     96,431,000 3,250
Securities Purchase Agreement, Price Per Share                                     $ 0.07 $ 1,000
Securities Purchase Agreement, Consideration Received On Transaction                                   9,700,000    
Organization and Summary of Significant Accounting Policies (Textual) [Abstract]                                        
Conversion Cap of Preferred Stock                           3.76% 0.00%          
Number of additional consideration of preferred shares in contingency                               8,205        
Percentage of Series E Convertible Preferred Stock convertible into common stock in contingency                               20.00%        
Amount paid upon exercise of redemption rights           2,900,000                            
Exercise of Series C-2 Warrants for Preferred Shares           500,000                     500,000      
Number of shares           500                     500      
Organization and Summary of Significant Accounting Policies (Additional Textual) [Abstract]                                        
Accumulated deficit   (458,904,000)   (458,904,000)   (447,366,000) (439,629,000)                          
Cash and cash equivalents   10,700,000 3,363,000 10,700,000 3,363,000 3,405,000 5,040,000         6,866,000                
Securities Purchase Agreement date           May 24, 2010                            
Number of trading days           3 days                            
Common stock, par value   $ 0.0001   $ 0.0001   $ 0.0001 $ 0.0001           $ 0.0001           $ 0.0001  
Percentage of issued and outstanding common stock           9.999%                            
Series of C-12 stock , Period of business days           10 days                            
Series C-1 preferred stock Consent and Amendment Agreement date           Mar. 29, 2011                            
Number of newly designated series of preferred stock           five                            
Operating costs of company           712,000                            
Reverse stock split ratio           100   0.0001 0.0001 100 0.0001                  
Estimated useful lives of the assets           5 years                            
Property and Equipment           2,186,000                            
Depreciation expense       3,000 0 0 0                          
Pre-vesting forfeitures were estimated for employees           0.00% 0.00%                          
Share-based compensation expense   2,742,000 2,962,000 8,568,000 5,672,000 8,604,000 254,000                          
Weighted-average fair value of options granted           $ 0.06 $ 0                          
Convertible preferred stock for initial proceeds $ 6,003,000                                      
Potentially dilutive securities for the exercise of outstanding stock options and warrants for common stock       657,000,000   4,500,000,000 6,700,000,000                          
Number of business segments for the development of pharmaceutical products           1                            
Non-employee stock options outstanding             0