Securities Purchase Agreement (Details Textual) (USD $)	1 Months Ended		12 Months Ended
	Mar. 31, 2011	May 31, 2010	Dec. 31, 2012 Agreement	Dec. 31, 2011	Mar. 03, 2012	Feb. 29, 2012	Feb. 17, 2012	Jan. 19, 2012	May 07, 2011	Apr. 14, 2011	May 26, 2010
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, par value				$ 0.0001
Preferred stock, par value			$ 0.0001
Embedded Derivatives of accrued dividends payable				$ 15,270,000
Preferred stock, shares authorized			8,000,000
Warrant, net proceeds			500,000
Proceeds from warrants, shares			500
Shares converted to common stock				123,000
Reverse stock split ratio			100			0.0001	0.0001	100		0.0001
Securities Purchase Agreement (Additional Textual) [Abstract]
Percentage of investment of proceeds contributed by employee maximum		3.00%
Proceeds from issuance of derivative obligations		6,003,000
Common stock, par value			$ 0.0001	$ 0.0001							$ 0.0001
Common stock, stated price											$ 3.00
Proceeds from preferred stock per share											$ 1,000
Exercise price series D1 warrants preferred		$ 1,000
Exercise price series C2 warrants preferred		1,000
Additional cash payment for right to receive Series C2 Preferred after milestones	236,000
Stockholders redemption period			12 months
Preferred Stock holders waived their 12-month redemption right and the requirement for the company to keep net cash			2,900,000
Expiration Period of warrants			3 years
Initial conversion ratio of new preferred stock to common stock			6,667		213,083				166,667
Amount paid upon exercise of redemption rights				5,116,000
Preferred stock, liquidation preference price per share			$ 1,000
Extended Termination Date			3 years
Price per share of common stock discounted from the closing market prices				$ 0.27
Number of times company and purchasers entered into amendment agreements			2
Derivative liabilities				15,270,000
Maximum [Member]
Securities Purchase Agreement (Textual) [Abstract]
Conversion Price Percentage			3.76%
Minimum [Member]
Securities Purchase Agreement (Textual) [Abstract]
Minimum preferred stock outstanding if warrants are exercised			3,000
Preferred stock, shares outstanding			1,000
Ownership percentage			9.999%
Conversion Price Percentage			0.00%
Series C-2 Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			22,000
Preferred stock, shares issued			500
Preferred stock, shares outstanding			500
Cumulative dividends payable			15.00%
Series D-1 Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			5,134
Preferred stock, shares issued			4,615
Preferred stock, shares outstanding			4,615
Shares converted to common stock			16
Series D-2 Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			10,868
Series C-2 Warrants [Member]
Securities Purchase Agreement (Textual) [Abstract]
Total value of the embedded derivative				9,051,000
Embedded Derivatives of accrued dividends payable				3,785,000
Mandatory exercise of warrants upon achievement of the Preclinical Milestone	7,452,000
Mandatory exercise of warrants upon achievement of the Clinical milestone	3,194,000
Exercise Price Series D2 Warrants Preferred		$ 1,000
Securities Purchase Agreement (Additional Textual) [Abstract]
Derivative liabilities				3,785,000
Series C-2 Warrants [Member] | Maximum [Member]
Securities Purchase Agreement (Textual) [Abstract]
Increased number of warrants	10,646
Series C-2 Warrants [Member] | Minimum [Member]
Securities Purchase Agreement (Textual) [Abstract]
Increased number of warrants	10,268
Series D-1 Warrants [Member]
Securities Purchase Agreement (Textual) [Abstract]
Total value of the embedded derivative			0	2,539,000
Embedded Derivatives of accrued dividends payable				2,539,000
Securities Purchase Agreement (Additional Textual) [Abstract]
Derivative liabilities				2,539,000
Series D-2 Warrants [Member]
Securities Purchase Agreement (Textual) [Abstract]
Embedded Derivatives of accrued dividends payable				5,266,000
Securities Purchase Agreement (Additional Textual) [Abstract]
Derivative liabilities				5,266,000
Series C-1 Convertible Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Aggregate of common shares of company		5,134
Preferred stock, par value											$ 0.0001
Preferred stock, par value			$ 0.0001
Preferred stock, shares authorized			11,000
Preferred stock, shares issued			5,792
Preferred stock, shares outstanding			5,792
Series C-11 Preferred charged to general and administrative expense			5,792,000
Series D-1 Convertible Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Aggregate of common shares of company		5,134
Preferred stock, par value											$ 0.0001
Series C-1 Preferred [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, par value											$ 0.0001
Shares of Series C1 Preferred into common stock			340,851,000
Preferred stock, shares authorized			11,000
Preferred stock, shares issued			5,792	5,043							5,134
Number of preferred stock considered for dividends			84	74
Dividend per shares				$ 0.014
Preferred stock, shares outstanding			5,792	5,043
Preferred stock, shares issued upon conversion of warrants			31,000	588,000
Shares converted to common stock			18,000,000
Accrued dividends on the Series C-11 Preferred			84,000	74,000
Securities Purchase Agreement (Additional Textual) [Abstract]
Shares of Series C1 Preferred into common stock			340,851,000
Series C-2 Preferred [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			22,000
Preferred stock, shares issued			500
Warrant, net proceeds			500,000
Proceeds from warrants, shares			500
Preferred stock, shares outstanding			500
Series D-1 preferred
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, par value			$ 0.0001	$ 0.0001
Shares of Series C1 Preferred into common stock			983,419,000
Preferred stock, shares authorized			5,134
Preferred stock, shares issued			4,615
Preferred stock, shares outstanding			4,615
Series C-11 Preferred charged to general and administrative expense			4,615,000
Securities Purchase Agreement (Additional Textual) [Abstract]
Shares of Series C1 Preferred into common stock			983,419,000
Series D-2 Preferred [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			10,868
Common Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Aggregate of common shares of company		289,704
Series C-1 Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, shares authorized			11,000
Preferred stock, shares issued			5,793	5,043
Preferred stock, shares outstanding			5,793	5,043
Series C-2 Convertible Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Number of warrants series C2 to be purchased		10,268
Preferred stock, par value			$ 0.0001	$ 0.0001							$ 0.0001
Preferred stock, shares authorized			22,000	22,000
Preferred stock, shares issued			500
Preferred stock, shares outstanding			500
Series C-11 Preferred charged to general and administrative expense			$ 500,000
Series D-2 Convertible Preferred Stock [Member]
Securities Purchase Agreement (Textual) [Abstract]
Preferred stock, par value											$ 0.0001