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Organization and Summary of Significant Accounting Policies (Details Textual) (USD $)
1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended
May 31, 2010
Dec. 31, 2012
Segment
Dec. 31, 2011
Feb. 29, 2012
Feb. 17, 2012
Jan. 19, 2012
Apr. 14, 2011
Dec. 31, 2010
May 26, 2010
Dec. 31, 2012
Maximum [Member]
Dec. 31, 2012
Minimum [Member]
Mar. 31, 2011
Series E Convertible Preferred Stock [Member]
Dec. 31, 2012
Series C-2 Preferred [Member]
Organization and Summary of Significant Accounting Policies (Textual) [Abstract]                          
Conversion Cap of Preferred Stock                   3.76% 0.00%    
Number of additional consideration of preferred shares in contingency                       8,205  
Percentage of Series E Convertible Preferred Stock convertible into common stock in contingency                       20.00%  
Amount paid upon exercise of redemption rights   $ 2,900,000                      
Exercise of Series C-2 Warrants for Preferred Shares   500,000                     500,000
Number of shares   500                     500
Organization and Summary of Significant Accounting Policies (Additional Textual) [Abstract]                          
Accumulated deficit   (447,366,000) (439,629,000)                    
Cash and cash equivalents   3,405,000 5,040,000         6,866,000          
Securities Purchase Agreement date   May 24, 2010                      
Number of trading days   3 days                      
Common stock, par value   $ 0.0001 $ 0.0001           $ 0.0001        
Percentage of issued and outstanding common stock   9.999%                      
Series of C-12 stock , Period of business days   10 days                      
Series C-1 preferred stock Consent and Amendment Agreement date   Mar. 29, 2011                      
Number of newly designated series of preferred stock   Five                      
Operating costs of company   712,000                      
Reverse stock split ratio   100   0.0001 0.0001 100 0.0001            
Estimated useful lives of the assets   5 years                      
Property and Equipment   2,186,000 2,186,000                    
Depreciation expense   0 0                    
Pre-vesting forfeitures were estimated for employees   0.00% 0.00%                    
Share-based compensation expense   8,604,000 254,000                    
Weighted-average fair value of options granted   $ 0.06                       
Convertible preferred stock for initial proceeds $ 6,003,000                        
Potentially dilutive securities for the exercise of outstanding stock options and warrants for common stock   4,500,000,000 6,700,000,000                    
Number of business segments for the development of pharmaceutical products   1                      
Non-employee stock options outstanding     0