Organization and Summary of Significant Accounting Policies (Details) (USD $)	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011
Summary of share-based compensation expense related to share-based awards
Share-based compensation expense included in operating expenses	$ 8,604,000	$ 254,000
Share-based compensation expense from:
Stock options	7,640,000	254,000
Restricted stock awards and restricted stock units	964,000
Share-based compensation expense included in operating expenses	8,604,000	254,000
Research and development [Member]
Summary of share-based compensation expense related to share-based awards
Share-based compensation expense included in operating expenses	805,000
General and administrative [Member]
Summary of share-based compensation expense related to share-based awards
Share-based compensation expense included in operating expenses	$ 7,799,000	$ 254,000