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Stockholders' Equity (Details Textual) (USD $)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 1 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended
Apr. 30, 2012
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Apr. 11, 2012
Apr. 10, 2012
May 31, 2008
Sep. 30, 2012
Research and development [Member]
Sep. 30, 2012
Research and development [Member]
Sep. 30, 2012
General and administrative [Member]
Sep. 30, 2011
General and administrative [Member]
Sep. 30, 2012
General and administrative [Member]
Sep. 30, 2011
General and administrative [Member]
Sep. 30, 2012
Director [Member]
Sep. 30, 2012
President and Chief Executive Officer and Employee [Member]
Sep. 30, 2012
Restricted Stock [Member]
Sep. 30, 2012
Restricted Stock [Member]
Research and development [Member]
Sep. 30, 2012
Restricted Stock [Member]
Research and development [Member]
Sep. 30, 2012
Restricted Stock [Member]
General and administrative [Member]
Sep. 30, 2012
Restricted Stock [Member]
General and administrative [Member]
Aug. 31, 2012
Restricted Stock Units [Member]
Apr. 30, 2012
Restricted Stock Units [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Aug. 20, 2012
Restricted Stock Units [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Research and development [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Research and development [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
General and administrative [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
General and administrative [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Director [Member]
Apr. 10, 2012
Restricted Stock Units [Member]
Director [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Employee [Member]
Apr. 10, 2012
Restricted Stock Units [Member]
Employee [Member]
Sep. 30, 2012
Restricted Stock Units [Member]
Consultant [Member]
Aug. 17, 2012
Restricted Stock Units [Member]
Consultant [Member]
Aug. 12, 2010
Maximum [Member]
Aug. 12, 2010
Minimum [Member]
Sep. 30, 2012
ESPP [Member]
Dec. 31, 2011
ESPP [Member]
Sep. 30, 2012
1994 Plan [Member]
Sep. 30, 2012
2004 Plan [Member]
Oct. 01, 2012
2010 Plan [Member]
Sep. 30, 2012
2010 Plan [Member]
Apr. 11, 2012
2010 Plan [Member]
Stockholders' Equity (Textual) [Abstract]                                                                                          
Common Stock authorized for issuance   12,008,000,000   12,008,000,000   6,008,000,000                                                                     164 640   1,188,414  
Options outstanding   592,230,570   592,230,570   894                                                                     8 75   16  
Shares remaining available for grants                                                                                 0 537   1,236,202  
Period of share-based payment awards                                                 36 months                                 10 years      
Additional common shares authorized                                                                                     120,520 47,804 676,640,705
Maximum percentage of the base salary of which an employee can purchase common stock                                                                             10.00%            
Common stock are reserved for issuance upon exercise of the warrants   390   390                                                                         593,467,889 593,467,889   593,467,889  
Unamortized share-based compensation expense                                   $ 70,000                         $ 184,000   $ 702                        
Share-based compensation expense option issued                               4 months 40 months               4 months                                        
Increase in the shares of common stock authorized for issuance under the Employee Stock Purchase Plan                                                                         485 85              
Share-based compensation expense   2,962,000 63,000 5,672,000 194,000         279,000 526,000 2,683,000 63,000 5,146,000 194,000       12,000 23,000 46,000 86,000         55 151 159,000 439,000                              
Restricted stock units granted                                                               10,360,892   14,219   2,700,000                  
Contingent right to receive share of common stock                                                 1                                        
Percentage of RSUs for employee vest                                                 25.00% 45.50%                                      
Restricted stock units weighted average grant date value                                             $ 0.069 $ 0.06                                          
Shares issued under Employee Stock Purchase Plan                                                                             0 0          
Shares of common stock issued and outstanding             10.00%                                                                            
Unamortized share-based compensation expense   30,428,000   30,428,000                       444,000 29,984,000                                   81,000                    
Stockholders' Equity (Additional Textual) [Abstract]                                                                                          
Issued warrants to purchase shares                 390                                                                        
Exercise price of Warrants granted   2,150   2,150                                                                                  
Term of common stock warrants       5 years                                                                                  
Outstanding warrants   390   390                                                                                  
Common stock offered for purchase to employee               592,230,471                                                                          
Options granted at exercise price               $ 0.06                                                                          
Percentage of grants vesting at one year anniversary of option award               25.00%                                                                          
Options exercisable have a weighted-average remaining contractual term       9 years 6 months 11 days                                                                                  
Common stock for options outstanding and exercisable intrinsic value   0   0   0                                                                              
Percentage of common stock market value used for purchase price of Employee Stock Purchase Plan   85.00%   85.00%                                                                                  
Maximum offer period for share purchase       24 months                                                                                  
Shares issued under the Employee Stock Purchase Plan   0   0   0                                                                              
Purchase of common stock, shares   72   72                                                                                  
Common stock available for future issuance   413   413                                                                                  
Restricted shares 2,987,850                                                                                        
Vesting period of two grants       3 years                                                                                  
Vesting period of the other grant       1 year                                                                                  
Stock option exercises           $ 0                                                                              
Restricted shares vesting date   Jan. 19, 2013   Jan. 19, 2013