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Stockholders' Equity (Details 3) (USD $)	3 Months Ended		9 Months Ended
Stockholders' Equity (Details 3) (USD $)	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category
Share-based compensation expense	$ 2,962,000	$ 63,000	$ 5,672,000	$ 194,000
Research and development [Member]
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category
Share-based compensation expense	279,000		526,000
General and administrative [Member]
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category
Share-based compensation expense	$ 2,683,000	$ 63,000	$ 5,146,000	$ 194,000

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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