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Stockholder's Equity (Details Textual) (USD $)
1 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 1 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 6 Months Ended 12 Months Ended 6 Months Ended
Apr. 30, 2012
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Apr. 11, 2012
Apr. 10, 2012
Dec. 31, 2011
May 31, 2008
Jun. 30, 2012
Research and development [Member]
Jun. 30, 2012
Research and development [Member]
Jun. 30, 2012
General and administrative [Member]
Jun. 30, 2011
General and administrative [Member]
Jun. 30, 2012
General and administrative [Member]
Jun. 30, 2011
General and administrative [Member]
Jun. 30, 2012
Director [Member]
Jun. 30, 2012
Chief Executive Officer [Member]
Jun. 30, 2012
President and Chief Executive Officer and Employee [Member]
Jun. 30, 2012
Restricted Stock [Member]
Jun. 30, 2012
Restricted Stock [Member]
Research and development [Member]
Jun. 30, 2012
Restricted Stock [Member]
Research and development [Member]
Jun. 30, 2012
Restricted Stock [Member]
General and administrative [Member]
Jun. 30, 2012
Restricted Stock [Member]
General and administrative [Member]
Apr. 30, 2012
Restricted Stock Units [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
Research and development [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
Research and development [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
General and administrative [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
General and administrative [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
Director [Member]
Apr. 10, 2012
Restricted Stock Units [Member]
Director [Member]
Jun. 30, 2012
Restricted Stock Units [Member]
Employee [Member]
Apr. 10, 2012
Restricted Stock Units [Member]
Employee [Member]
Aug. 12, 2010
Maximum [Member]
Aug. 12, 2010
Minimum [Member]
Jun. 30, 2012
ESPP [Member]
Dec. 31, 2011
ESPP [Member]
Jun. 30, 2012
1994 Plan [Member]
Jun. 30, 2012
2004 Plan [Member]
Jun. 30, 2012
2010 Plan [Member]
Apr. 11, 2012
2010 Plan [Member]
Stockholder's Equity (Textual) [Abstract]                                                                                  
Issued warrants to purchase shares                 390                                                                
Exercise price of Warrants granted   21,500   21,500                                                                          
Term of common stock warrants       5 years                                                                          
Outstanding warrants   $ 390   $ 390                                                                          
Common stock are reserved for issuance upon exercise of the warrants   390   390                                                                          
Common Stock authorized for issuance   12,008,000,000   12,008,000,000       6,008,000,000                                                           164 640 1,188,414  
Options outstanding   592,230,573   592,230,573       894                                                           11 75 16  
Stock option exercises       0                                                                          
Shares remaining available for grants                                                                             537 1,188,398  
Period of share-based payment awards                                                 36 months                           10 years    
Additional common shares authorized                                                                               47,805 676,640,705
Maximum percentage of the base salary of which an employee can purchase common stock                                                                       10.00%          
Options exercisable have a weighted-average remaining contractual term       9 years 9 months 11 days                                                                          
Common stock for options outstanding and exercisable intrinsic value   0   0       0                                                                  
Common stock offered for purchase to employee             592,230,471                                                                    
Options granted at exercise price             $ 0.06                                                                    
Vesting period of two grants       3 years                                                                          
Vesting period of the other grant       1 year                                                                          
Percentage of grants vesting at one year anniversary of option award             25.00%                                                                    
Percentage of common stock market value used for purchase price of Employee Stock Purchase Plan   85.00%   85.00%                                                                          
Maximum offer period for share purchase       24 months                                                                          
Increase in the shares of common stock authorized for issuance under the Employee Stock Purchase Plan                                                                   485 85            
Restricted shares 2,987,850                                                                                
Shares issued under the Employee Stock Purchase Plan   0   0                                                                          
Purchase of common stock, shares   72   72                                                                          
Common stock available for future issuance   413   413                                                                          
Restricted shares vesting date   Jan. 19, 2013   Jan. 19, 2013                                                                          
Shares issued under Employee Stock Purchase Plan                                                                       0 0        
Shares of common stock issued and outstanding           10.00%                                                                      
Unamortized share-based compensation expense   33,080,000   33,080,000                       809,000   32,271,000                                              
Unamortized share-based compensation expense                                     128,000                     342,000   1,000                  
Share-based compensation expense option issued                               7 months 7 months 42 months             7 months                                
share-based compensation expense   $ 2,710,000 $ 63,000 $ 2,710,000 $ 131,000         $ 248,000 $ 248,000 $ 2,462,000 $ 63,000 $ 2,462,000 $ 131,000         $ 11,000 $ 10,691 $ 40,000 $ 40,259     $ 0 $ 0 $ 280,000 $ 279,744                        
Restricted stock units granted                                                             10,360,892   14,219                
Contingent right to receive share of common stock                                                 1                                
Percentage of RSUs for employee vest                                                 25.00%                                
Restricted stock units weighted average grant date value                                               $ 0.06