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Stockholder's Equity (Details 3) (USD $)
3 Months Ended 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category        
share-based compensation expense $ 2,710,000 $ 63,000 $ 2,710,000 $ 131,000
Research and development [Member]
       
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category        
share-based compensation expense 248,000   248,000  
General and administrative [Member]
       
Summary of share-based compensation expense related to stock options, restricted stock and restricted stock units by expense category        
share-based compensation expense $ 2,462,000 $ 63,000 $ 2,462,000 $ 131,000