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Unaudited Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2020
Mar. 31, 2020
Jun. 30, 2019
Mar. 31, 2019
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2018
Jun. 30, 2020
Dec. 31, 2019
Jun. 30, 2019
Operating activities                    
Net loss $ (15,592) $ (8,591) $ (30,416) $ (31,685) $ (24,183) $ (62,101) $ (62,101)      
Adjustments to reconcile net loss to net cash used for operating activities:                    
Share-based compensation expense 1,590 2,407 6,321 6,782 3,997          
Share-based compensation expense           13,103        
Depreciation and amortization expense         1,798 2,263        
Loss on disposal of equipment         904 15        
Unrealized gains on short-term investments         (63) 0        
Non-cash interest expense         3,392 4,678        
Non-cash rent expense         699 639        
Changes in operating assets and liabilities:                    
Accounts receivable, net         1,117 (512)        
Inventory, net         (909) 52        
Prepaid expenses and other current assets         1,675 22        
Accounts payable         (1,696) (3,664)        
Accrued expenses         (3,378) 974        
Accrued payroll and related expenses         (2,591) (3,429)        
Lease liability         (1,357) (1,241)        
Net cash used for operating activities         (20,595) (49,201)        
Investing activities                    
Proceeds from the sale of property and equipment         2,860 0        
Purchases of property and equipment         0 (441)        
Purchases of short-term investments         (2,999) 0        
Net cash used for investing activities         (139) (441)        
Financing activities                    
Net proceeds from issuance of common stock under 2013 Equity Plan         605 0        
Net proceeds from issuance of common stock under ESPP         359 484        
Net cash provided by financing activities         964 484        
Net decrease in cash and restricted cash         (19,770) (49,158)        
Cash and restricted cash at beginning of period   88,729   173,513 88,729 173,513        
Cash and restricted cash at end of period 68,959   124,355   68,959 124,355 173,513      
Supplemental disclosure of non-cash investing and financing activities:                    
Conversion of Series F Convertible Preferred Stock into common stock         0 2,737        
Cumulative-effect adjustment from adoption of ASU 2018-07               $ 0   $ (160)
Initial recognition of right-of-use lease asset         0 16,798        
Reconciliation of cash and restricted cash to the condensed consolidated balance sheets                    
Cash               68,353 $ 87,820 123,446
Restricted cash               606   909
Total cash and restricted cash $ 68,959 $ 88,729 $ 124,355 $ 173,513 $ 68,959 $ 124,355 $ 173,513 $ 68,959 $ 88,729 $ 124,355