Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2020	Dec. 31, 2019
Current assets:
Cash	$ 68,353	$ 87,820
Short-term investments	3,062	0
Accounts receivable, net	1,843	2,960
Inventory, net	3,120	2,211
Prepaid expenses and other current assets	2,792	4,467
Total current assets	79,170	97,458
Property and equipment, net	12,827	18,389
Right-of-use lease asset	14,792	15,491
Restricted cash	606	909
Total assets	107,395	132,247
Current liabilities:
Accounts payable	2,481	4,177
Accrued expenses	6,772	9,312
Accrued payroll and related expenses	5,741	8,332
Lease liability, current portion	2,890	2,766
Total current liabilities	17,884	24,587
Lease liability, less current portion	25,000	26,481
Deferred royalty obligation, net	124,406	124,379
Other noncurrent liabilities	15,317	12,790
Total liabilities	182,607	188,237
Shareholders’ deficit:
Common Stock, $0.0001 par value; 100,000,000 shares authorized, 27,358,611 and 27,195,469 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively	3	3
Additional paid-in capital	982,393	977,432
Accumulated deficit	(1,061,514)	(1,037,331)
Total shareholders’ deficit	(75,212)	(55,990)
Total liabilities and shareholders’ deficit	107,395	132,247
Series C-1 Convertible Preferred Stock [Member]
Shareholders’ deficit:
Series C-12 Convertible Preferred Stock, $0.0001 par value; 11,000 shares authorized, 3,906 shares issued and outstanding at June 30, 2020 and December 31, 2019; and liquidation preference of $3,906 at June 30, 2020 and December 31, 2019	$ 3,906	$ 3,906