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Deferred Royalty Obligation (Details) - USD ($)
3 Months Ended 12 Months Ended
May 10, 2018
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Dec. 31, 2018
Debt Instrument [Line Items]          
Deferred royalty obligation, net   $ 124,392,000   $ 124,379,000  
Interest expense   2,400,000 $ 2,700,000    
Royalty Obligation Payable       800,000  
HealthCare Royalty Partners          
Debt Instrument [Line Items]          
Proceeds from royalty agreement $ 125,000,000.0        
Required payment for breach of agreement, payment one 125,000,000.0        
Required payment for breach of agreement, payment two 225,000,000.0        
HealthCare Royalty Partners | Loans Payable | Royalty Financing Agreement          
Debt Instrument [Line Items]          
Deferred royalty obligation, net 125,000,000.0 $ 124,400,000      
Debt issuance costs $ 700,000        
Unamortized debt discount       600,000  
Accrued interest expense       17,200,000 $ 15,500,000
Royalty payments       700,000  
HealthCare Royalty Partners | Period One          
Debt Instrument [Line Items]          
Maximum potential royalty payout 10.00%        
HealthCare Royalty Partners | Period Two          
Debt Instrument [Line Items]          
Increase in maximum potential payout percent 4.00%        
HealthCare Royalty Partners | Payout Period          
Debt Instrument [Line Items]          
Increase in maximum potential payout percent 4.00%        
Other Noncurrent Liabilities | HealthCare Royalty Partners | Loans Payable | Royalty Financing Agreement          
Debt Instrument [Line Items]          
Accrued interest expense       $ 13,700,000 $ 12,800,000