Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2020	Dec. 31, 2019
Current assets:
Cash	$ 77,219	$ 87,820
Accounts receivable, net	3,552	2,960
Inventory, net	1,960	2,211
Prepaid expenses and other current assets	3,383	4,467
Total current assets	86,114	97,458
Property and equipment, net	16,038	18,389
Right-of-use lease asset	15,146	15,491
Restricted cash	909	909
Total assets	118,207	132,247
Current liabilities:
Accounts payable	1,895	4,177
Accrued expenses	7,675	9,312
Accrued payroll and related expenses	3,649	8,332
Lease liability, current portion	2,828	2,766
Total current liabilities	16,047	24,587
Lease liability, less current portion	25,745	26,481
Deferred royalty obligation, net	124,392	124,379
Other noncurrent liabilities	13,692	12,790
Total liabilities	179,876	188,237
Shareholders’ deficit:
Common Stock, $0.0001 par value; 100,000,000 shares authorized, 27,276,734 and 27,195,469 shares issued and outstanding at March 31, 2020 and December 31, 2019, respectively	3	3
Additional paid-in capital	980,344	977,432
Accumulated deficit	(1,045,922)	(1,037,331)
Total shareholders’ deficit	(61,669)	(55,990)
Total liabilities and shareholders’ deficit	118,207	132,247
Series C-1 Convertible Preferred Stock [Member]
Shareholders’ deficit:
Series C-12 Convertible Preferred Stock, $0.0001 par value; 11,000 shares authorized, 3,906 shares issued and outstanding at March 31, 2020 and December 31, 2019; and liquidation preference of $3,906 at March 31, 2020 and December 31, 2019	$ 3,906	$ 3,906