Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Revenue
Net product sales	$ 23,054	$ 10,056
Total revenue	23,054	10,056
Operating expenses
Cost of product sales	2,392	1,643
Research and development	85,329	117,302
Selling, general and administrative	45,134	85,162
Total operating expenses	132,855	204,107
Loss from operations	(109,801)	(194,051)
Interest expense	10,774	7,303
Interest income	2,128	1,885
Other income—related party	1,939	0
Total other (expense) income, net	(6,707)	(5,418)
Net loss	$ (116,508)	$ (199,469)
Basic and diluted net loss per share (usd per share)	$ (4.30)	$ (7.85)
Weighted-average common shares outstanding - basic and diluted (in shares)	27,112	25,422