Unaudited Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Revenue
Net product sales	$ 4,395	$ 809
Total revenue	4,395	809
Operating expenses
Cost of product sales	500	58
Research and development	21,244	28,429
Selling, general and administrative	12,320	23,016
Total operating expenses	34,064	51,503
Loss from operations	(29,669)	(50,694)
Interest expense	(2,729)	0
Interest income	713	166
Total other (expense) income, net	(2,016)	166
Net loss	$ (31,685)	$ (50,528)
Net loss per share, basic and diluted (usd per share)	$ (1.17)	$ (2.22)
Weighted-average common shares outstanding - basic and diluted (in shares)	27,035	22,742