Unaudited Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenue
Net product sales	$ 809	$ 0
Total revenue	809	0
Operating expenses
Cost of product sales	58	0
Research and development	28,429	17,765
Selling, general and administrative	23,016	5,503
Total operating expenses	51,503	23,268
Loss from operations	(50,694)	(23,268)
Other income, net	166	28
Net loss	$ (50,528)	$ (23,240)
Net loss per share, basic and diluted (usd per share)	$ (2.22)	$ (1.26)
Weighted-average common shares outstanding - basic and diluted (in shares)	22,742	18,410