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Shareholders’ Equity (Stock Option and Restricted Stock Award Activity) (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Shares Underlying Stock Options and Restricted Stock Awards      
Outstanding beginning balance, Shares underlying stock options and restricted stock awards (in shares) 2,318,685 618,900 54,000
Granted, Shares underlying stock options and restricted stock awards (in shares) 483,200 1,769,785 567,876
Restricted stock awards vested, Shares underlying stock options and restricted stock awards (in shares)     (2,976)
Exercised, Shares underlying stock options and restricted stock awards (in shares) (17,548) (51,814) 0
Forfeited, Shares underlying stock options and restricted stock awards (in shares) (156,875) (18,186)  
Outstanding ending balance, Shares underlying stock options and restricted stock awards (in shares) 2,627,462 2,318,685 618,900
Vested and expected to vest ending balance, Shares underlying stock options (in shares) 2,627,462    
Exercisable ending balance, Shares underlying stock options (in shares) 1,105,029    
Weighted-Average Exercise Price per Share      
Outstanding beginning balance, Weighted - average exercise price (in dollars per share) $ 22.01 $ 9.54 $ 6.00
Granted, Weighted - average exercise price (in dollars per share) 17.83 25.89 9.88
Vested, Weighted - average exercise price (in dollars per share)     0.00
Exercised, Weighted - average exercise price (in dollars per share) 8.52 10.81  
Forfeited, Weighted - average exercise price (in dollars per share) 26.35 7.80  
Outstanding ending balance, Weighted - average exercise price (in dollars per share) 21.07 $ 22.01 $ 9.54
Vested and expected to vest ending balance, Weighted - average exercise price (in dollars per share) 21.07    
Exercisable ending balance, Weighted - average exercise price (in dollars per share) $ 20.45    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]      
Outstanding ending balance, Weighted - average remaining contractual term (yrs) 8 years 4 months 20 days    
Outstanding ending balance, Aggregate intrinsic value $ 4,307,756    
Vested and expected to vest ending balance, Weighted - average remaining contractual term (yrs) 8 years 4 months 20 days    
Vested and expected to vest ending balance, Aggregate intrinsic value $ 4,307,756    
Exercisable ending balance, Weighted - average remaining contractual term (yrs) 7 years 10 months 5 days    
Exercisable ending balance, Aggregate intrinsic value $ 2,740,900