Unaudited Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended	9 Months Ended
Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenue
Contract revenue - related party	$ 44	$ 647	$ 531	$ 647
Total revenue	44	647	531	647
Expenses
Research and development	16,992	7,781	42,111	19,637
General and administrative	4,349	3,353	11,868	11,122
Total expenses	21,341	11,134	53,979	30,759
Loss from operations	(21,297)	(10,487)	(53,448)	(30,112)
Other income, net	46	13	150	33
Net loss	$ (21,251)	$ (10,474)	$ (53,298)	$ (30,079)
Basic and diluted net loss per share (usd per share)	$ (1.23)	$ (0.70)	$ (3.10)	$ (1.99)
Shares used in computing basic and diluted net loss per share (in shares)	17,211	14,899	17,211	15,129

Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income. Excludes changes in equity resulting from investments by owners and distributions to owners.

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