Commitments and Contingencies

12 Months Ended

Dec. 31, 2015

Commitments and Contingencies Disclosure [Abstract]

Leases

In January 2015, the Company entered into a 25-month lease agreement for 4,047 square feet of lab space. The lease term is from March 2015 through March 2017, and the Company's total remaining lease payments through the end of the lease will be approximately $57,000.

In February 2015, the Company entered into a 32-month sublease agreement, as a sublessee, for 18,599 square feet of office space to be used as the Company's corporate headquarters. The lease term is through October 2017, and the Company's total remaining lease payments through the end of the lease will be approximately $1,017,000. The Company also leases a total of 3,713 square feet of office space with a lease term through March 2018, and total remaining lease payments through the end of the lease are approximately $317,000.

Annual future minimum payments under operating leases as of December 31, 2015 were as follows (in thousands):



	Operating Leases		Sublease Income			Net Operating Leases
2016	$	729	$	(68	)	$	661
2017	626		(74		)	552
2018	36		(19		)	17
Total minimum lease payments	$	1,391	$	(161	)	$	1,230

Rent expense was $699,000, $176,000 and $84,000 for the years ended December 31, 2015, 2014 and 2013, respectively.

Licensing Agreements

In the normal course of business, the Company enters into licensing agreements under which the Company commits to certain annual maintenance payments. Annual future minimum licensing payments under the Company's agreements as of December 31, 2015 are as follows (in thousands):



	Minimum Payments
2016	$	75
2017	75
2018	85
2019	23
2020	23
Thereafter	85
Total minimum annual maintenance fee payments	$	366