Exhibit 32.1

Certification Under Section 906 of the Sarbanes-Oxley Act of 2002

(18 U.S.C., Section 1350)

In connection with the Annual Report on Form 10-K of Virtu ITG Holdings LLC (the "Company") for the year ended December 31, 2018, as filed with the SEC on the date hereof (the "Report"), Douglas A. Cifu, as Chief Executive Officer of the Company, and Joseph Molluso, as Chief Financial Officer of the Company, each hereby certifies, pursuant to 18 U.S.C. §1350, that to his knowledge:

(1)          The Report fully complies with the requirements of Section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended (the "Exchange Act"); and

(2)          The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

/s/ Douglas A. Cifu	/s/ Joseph Molluso
Douglas A. Cifu	Joseph Molluso
Chief Executive Officer	Chief Financial Officer
March 14, 2019	March 14, 2019

The foregoing certification is being furnished solely pursuant to 18 U.S.C. § 1350 and shall not be deemed filed by the Company for purposes of Section 18 of the Exchange Act. Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.