Exhibit 16.1

February 7, 2011

Office of the Chief Accountant
Securities and Exchange Commission
100 F Street, N. E.
Washington, D.C. 20549

Ladies and Gentlemen:

We have read the comments made regarding us in Item 4.01 of Form 8-K of Fentura Financial Corporation, Inc., dated February 4, 2011 and filed February 10, 2011, as contained in the first and second paragraphs of Item 4.01, and are in agreement with those statements.

/s/ Crowe Horwath LLP  

Crowe Horwath LLP 

Grand Rapids, Michigan 

cc: Douglas Rotman
Audit Committee Chairman
Fentura Financial, Inc.