-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 uP1q8t2ymzg9V8MOSLoh6A==

<SEC-DOCUMENT>0000919567-08-000021.txt : 20081112
<SEC-HEADER>0000919567-08-000021.hdr.sgml : 20081111
<ACCEPTANCE-DATETIME>20081112173022
ACCESSION NUMBER:		0000919567-08-000021
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20081001
FILED AS OF DATE:		20081112
DATE AS OF CHANGE:		20081112

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INTEGRATED SECURITY SYSTEMS INC
		CENTRAL INDEX KEY:			0000741114
		STANDARD INDUSTRIAL CLASSIFICATION:	COMMUNICATIONS EQUIPMENT, NEC [3669]
		IRS NUMBER:				752422983
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		8200 SPRINGWOOD DR STE 230
		CITY:			IRVING
		STATE:			TX
		ZIP:			75063
		BUSINESS PHONE:		9724448280

	MAIL ADDRESS:	
		STREET 1:		8200 SPRINGWOOD DR SUITE 230
		CITY:			IRVING
		STATE:			TX
		ZIP:			75063

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RENAISSANCE CAPITAL GROWTH & INCOME FUND III INC
		CENTRAL INDEX KEY:			0000919567
		STATE OF INCORPORATION:			TX
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-11900
		FILM NUMBER:		081181962

	BUSINESS ADDRESS:	
		STREET 1:		8080 N CENTRAL EXPRWY
		STREET 2:		STE 210 LB59
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75206
		BUSINESS PHONE:		2148918294

	MAIL ADDRESS:	
		STREET 1:		8080 N CENTRAL EXPWY., SUITE 210 LB 59
		CITY:			DALLAS
		STATE:			TX
		ZIP:			75206
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4izzirenn3_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-10-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000741114</issuerCik>
        <issuerName>INTEGRATED SECURITY SYSTEMS INC</issuerName>
        <issuerTradingSymbol>IZZI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000919567</rptOwnerCik>
            <rptOwnerName>RENAISSANCE CAPITAL GROWTH &amp; INCOME FUND III INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>8080 N CENTRAL EXPWY., SUITE 210 LB 59</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>DALLAS</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>75206</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>common stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1638222</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>48898.58</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>39626430</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">shares paid in kind for interest for August to October 2008; 264,231 shares @ .02 for August 2008; 170,472 shares @ .03 for
 September 2008; 1,203,519 shares @ .03 for October 2008</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Russell Cleveland</signatureName>
        <signatureDate>2008-11-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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