-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 DeXQt9GIS4n/2WXrpIZ8F19AF078aXLLvVjNS45n/CpRMFEFTNnwu7ufyiqT37oY
 LFM6wtt8pOi+ucyHyUspIA==

<SEC-DOCUMENT>0000898432-08-000609.txt : 20080626
<SEC-HEADER>0000898432-08-000609.hdr.sgml : 20080626
<ACCEPTANCE-DATETIME>20080626174516
ACCESSION NUMBER:		0000898432-08-000609
CONFORMED SUBMISSION TYPE:	3/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071030
FILED AS OF DATE:		20080626
DATE AS OF CHANGE:		20080626

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NEUROBIOLOGICAL TECHNOLOGIES INC /CA/
		CENTRAL INDEX KEY:			0000918112
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				943049219
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		2000 POWELL STREET, SUITE 800
		CITY:			EMERYVILLE
		STATE:			CA
		ZIP:			94608
		BUSINESS PHONE:		510-595-6000

	MAIL ADDRESS:	
		STREET 1:		2000 POWELL STREET,  SUITE 800
		CITY:			EMERYVILLE
		STATE:			CA
		ZIP:			94608

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BVF PARTNERS L P/IL
		CENTRAL INDEX KEY:			0001055947

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23280
		FILM NUMBER:		08920242

	BUSINESS ADDRESS:	
		STREET 1:		ONE SANSOME ST
		STREET 2:		39TH FL
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		3125066500

	MAIL ADDRESS:	
		STREET 1:		900 N. MICHIGAN AVENUE
		STREET 2:		SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BVF INVESTMENTS LLC
		CENTRAL INDEX KEY:			0001132245
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23280
		FILM NUMBER:		08920244

	BUSINESS ADDRESS:	
		STREET 1:		ONE SANSOME ST. 39TH FL
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		3125066500

	MAIL ADDRESS:	
		STREET 1:		C/O GROSVENOR CAPITAL MANAGEMENT LP
		STREET 2:		900 N. MICHIGAN AVENUE, SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BVF INC/IL
		CENTRAL INDEX KEY:			0001056807
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23280
		FILM NUMBER:		08920241

	BUSINESS ADDRESS:	
		STREET 1:		ONE SANSOME ST
		STREET 2:		39TH FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		3125066500

	MAIL ADDRESS:	
		STREET 1:		C/O GROSVENOR CAPITAL MANAGEMENT
		STREET 2:		900 N. MICHIGAN AVENUE, SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BIOTECHNOLOGY VALUE FUND L P
		CENTRAL INDEX KEY:			0000918923
		STANDARD INDUSTRIAL CLASSIFICATION:	INVESTMENT ADVICE [6282]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23280
		FILM NUMBER:		08920243

	BUSINESS ADDRESS:	
		STREET 1:		900 N. MICHIGAN AVENUE, SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611
		BUSINESS PHONE:		3125066500

	MAIL ADDRESS:	
		STREET 1:		900 N. MICHIGAN AVENUE, SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BIOTECHNOLOGY VALUE FUND II LP
		CENTRAL INDEX KEY:			0001102444
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23280
		FILM NUMBER:		08920240

	BUSINESS ADDRESS:	
		STREET 1:		ONE SANSOME ST
		STREET 2:		39TH FL.
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		3125066500

	MAIL ADDRESS:	
		STREET 1:		C/O GROSVENOR CAPITAL MANAGEMENT
		STREET 2:		900 N. MICHIGAN AVENUE, SUITE 1100
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60611
</SEC-HEADER>
<DOCUMENT>
<TYPE>3/A
<SEQUENCE>1
<FILENAME>bvf-form3a_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2007-10-30</periodOfReport>

    <dateOfOriginalSubmission>2007-11-02</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000918112</issuerCik>
        <issuerName>NEUROBIOLOGICAL TECHNOLOGIES INC /CA/</issuerName>
        <issuerTradingSymbol>NTII</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001055947</rptOwnerCik>
            <rptOwnerName>BVF PARTNERS L P/IL</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GROSVENOR CAPITAL MANAGEMENT LP</rptOwnerStreet1>
            <rptOwnerStreet2>900 N. MICHIGAN AVENUE, SUITE 1100</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60611</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Indirect Beneficial Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001056807</rptOwnerCik>
            <rptOwnerName>BVF INC/IL</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GROSVENOR CAPITAL MANAGEMENT LP</rptOwnerStreet1>
            <rptOwnerStreet2>900 N. MICHIGAN AVENUE, SUITE 1100</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60611</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Indirect Beneficial Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001102444</rptOwnerCik>
            <rptOwnerName>BIOTECHNOLOGY VALUE FUND II LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GROSVENOR CAPITAL MANAGEMENT LP</rptOwnerStreet1>
            <rptOwnerStreet2>900 N. MICHIGAN AVENUE, SUITE 1100</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60611</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Direct Beneficial Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000918923</rptOwnerCik>
            <rptOwnerName>BIOTECHNOLOGY VALUE FUND L P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GROSVENOR CAPITAL MANAGEMENT LP</rptOwnerStreet1>
            <rptOwnerStreet2>900 N. MICHIGAN AVENUE, SUITE 1100</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60611</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Direct Beneficial Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001132245</rptOwnerCik>
            <rptOwnerName>BVF INVESTMENTS LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GROSVENOR CAPITAL MANAGEMENT LP</rptOwnerStreet1>
            <rptOwnerStreet2>900 N. MICHIGAN AVENUE, SUITE 1100</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60611</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Direct Beneficial Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1230336</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>836807</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2824250</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F3"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4891393</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F4"/>
                    <footnoteId id="F6"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F4"/>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4891393</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F5"/>
                    <footnoteId id="F6"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F5"/>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The shares of Common Stock are directly beneficially owned by Biotechnology Value Fund, L.P., a Delaware limited partnership
 (&quot;BVF&quot;). The share amounts were originally reported incorrectly.</footnote>
        <footnote id="F2">The shares of Common Stock are directly beneficially owned by Biotechnology Value Fund II, L.P., a Delaware limited
 partnership (&quot;BVF2&quot;). The share amounts were originally reported incorrectly.</footnote>
        <footnote id="F3">The shares of Common Stock are directly beneficially owned by BVF Investments, L.L.C., a Delaware limited liability company
 (&quot;Investments&quot;). The share amounts were originally reported incorrectly.</footnote>
        <footnote id="F4">The shares of Common Stock are indirectly beneficially owned by BVF Partners L.P., a Delaware limited partnership
 (&quot;Partners&quot;). Partners is the general partner of BVF and BVF2, and is the manager of investments. The share amounts were
 originally reported incorrectly.</footnote>
        <footnote id="F5">The shares of Common Stock are indirectly beneficially owned by BVF Inc., a Delaware corporation (&quot;BVF Inc.&quot;), which is the
 general partner of Partners and is also an investment advisor to Partners. The share amounts were originally reported
 incorrectly.</footnote>
        <footnote id="F6">Pursuant to the operating agreement of Investments, Partners is authorized, among other things, to invest funds of Ziff Asset
 Management, L.P., the majority member of Investments, in the shares of Common Stock described herein and to vote and
 exercise dispositive power over those securities. Mark N. Lampert is the sole shareholder and sole director of BVF Inc., and
 is an officer of BVF Inc. This joint filing on Form 3 shall not be deemed an admission that Mark N. Lampert is, for purposes
 of Section 16 of the Securities and Exchange Act of 1934, as amended, or otherwise, the beneficial owner of any securities
 covered by this joint filing. Mr. Lampert disclaims beneficial ownership of all securities reported in this joint filing on
 Form 3, except to the extent that he has a pecuniary interest therein.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>BVF PARTNERS, L.P., by BVF Inc., its General Partner, By: /s/ Mark N. Lampert, President</signatureName>
        <signatureDate>2008-06-26</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BIOTECHNOLOGY VALUE FUND, L.P., by BVF Partners L.P., its General Partner, By: BVF Inc., its General Partner, By: /s/ Mark N. Lampert, President</signatureName>
        <signatureDate>2008-06-26</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BIOTECHNOLOGY VALUE FUND II, L.P., by BVF Partners L.P., its General Partner, By: BVF Inc., its General Partner, By: /s/ Mark N. Lampert, President</signatureName>
        <signatureDate>2008-06-26</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BVF INVESTMENTS, L.L.C., by BVF Partners, L.P., its Manager, By:  BVF Inc., its General Partner, By: /s/ Mark N. Lampert, President</signatureName>
        <signatureDate>2008-06-26</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BVF INC.,  By: /s/ Mark N. Lampert, President</signatureName>
        <signatureDate>2008-06-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----