Leases - Narrative (Details) - USD ($) $ in Thousands	1 Months Ended	9 Months Ended	12 Months Ended
	Mar. 31, 2020	Dec. 31, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Lessee, Lease, Description [Line Items]
Cumulative effect of new accounting principle in period of adoption		$ 254,152	$ 224,185	$ 254,152	$ 353,277	$ 419,271
Increase (decrease) in operating lease, right-of-use asset	$ (8,100)
Decrease in operating lease, liability, noncurrent	10,500
Decrease in operating lease, liability, current	600
Increase (decrease) in change between operating lease right-of-use assets and operating lease, liabilities	3,000
Loss on termination of lease	4,400
Impairment charge on termination of lease	$ 2,900
COVID-19
Lessee, Lease, Description [Line Items]
Lessee, operating lease, deferred lease payments		500
Increase (decrease) in cash savings			(200)	700
Adoption of new accounting standard
Lessee, Lease, Description [Line Items]
Cumulative effect of new accounting principle in period of adoption						(51)
Accumulated deficit
Lessee, Lease, Description [Line Items]
Cumulative effect of new accounting principle in period of adoption		$ (205,875)	$ (219,100)	$ (205,875)	$ (105,283)	(58,491)
Accumulated deficit | Adoption of new accounting standard
Lessee, Lease, Description [Line Items]
Cumulative effect of new accounting principle in period of adoption						$ (51)
Minimum | Equipment
Lessee, Lease, Description [Line Items]
Finance lease, term of contract			3 years
Operating lease, term of contract			2 years
Minimum | Manufacturing Facility
Lessee, Lease, Description [Line Items]
Operating lease, term of contract			3 years
Maximum | Equipment
Lessee, Lease, Description [Line Items]
Finance lease, term of contract			8 years
Operating lease, term of contract			5 years
Maximum | Manufacturing Facility
Lessee, Lease, Description [Line Items]
Operating lease, term of contract			20 years