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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 8lVFF3rYqNQJOgIC9nSXGA==

<SEC-DOCUMENT>0001164710-04-000031.txt : 20040218
<SEC-HEADER>0001164710-04-000031.hdr.sgml : 20040218
<ACCEPTANCE-DATETIME>20040218085613
ACCESSION NUMBER:		0001164710-04-000031
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040213
FILED AS OF DATE:		20040218

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IGEN INTERNATIONAL INC /DE
		CENTRAL INDEX KEY:			0000916304
		STANDARD INDUSTRIAL CLASSIFICATION:	PATENT OWNERS & LESSORS [6794]
		IRS NUMBER:				942852543
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		16020 INDUSTRIAL DR
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877
		BUSINESS PHONE:		3019848000

	MAIL ADDRESS:	
		STREET 1:		16020 INDUSTRIAL DRIVE
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IGEN INC /CA/
		DATE OF NAME CHANGE:	19931216

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CASS RICHARD W
		CENTRAL INDEX KEY:			0001118960
		STANDARD INDUSTRIAL CLASSIFICATION:	PATENT OWNERS & LESSORS [6794]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23252
		FILM NUMBER:		04611810

	BUSINESS ADDRESS:	
		STREET 1:		C/O
		STREET 2:		16020 INDUSTRIAL DR
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877
		BUSINESS PHONE:		3019848000

	MAIL ADDRESS:	
		STREET 1:		C/O
		STREET 2:		16020 INDUSTRIAL DRIVE
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>cass-form4_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2004-02-13</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0000916304</issuerCik>
        <issuerName>IGEN INTERNATIONAL INC /DE</issuerName>
        <issuerTradingSymbol>IGEN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001118960</rptOwnerCik>
            <rptOwnerName>CASS RICHARD W</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>16020 INDUSTRIAL DR</rptOwnerStreet1>
            <rptOwnerStreet2>16020 INDUSTRIAL DR</rptOwnerStreet2>
            <rptOwnerCity>GAITHERSBURG</rptOwnerCity>
            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>20877</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Option to Buy</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>15.69</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2004-02-13</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2000-06-27</value>
            </exerciseDate>
            <expirationDate>
                <value>2010-06-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Option to Buy</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>23.30</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2004-02-13</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2001-06-06</value>
            </exerciseDate>
            <expirationDate>
                <value>2011-06-06</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This option, which provided for vesting in installments, was cancelled pursuant to the terms of the Agreement and Plan of Merger (&quot;Agreement and Plan of Merger&quot;) dated July 24, 2003 among Roche Holding Ltd, 66 Acquisition Corporation II, IGEN International, Inc. and BioVeris Corporation (formerly known as IGEN Integrated Healthcare, LLC) and in accordance therewith, each share under this option was exchanged for a cash payment of $31.56 (representing the difference between the exercise price of
the option and $47.25 per share) plus one (1) share of common stock of BioVeris Corporation.  The Agreement and Plan of Merger is more fully described in the Registration Statement on Form S-4 (333-109196) as filed with the Securities and Exchange Commission on January 13, 2004.</footnote>
        <footnote id="F2">This option, which provided for vesting in installments, was cancelled pursuant to the terms of the Agreement and Plan of Merger, and in accordance therewith, each share under option was exchanged for a cash payment of $23.95 (representing the difference between the exercise price of the option and $47.25 per share) plus one (1) share of common stock of BioVeris Corporation.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/Richard W.Cass</signatureName>
        <signatureDate>2004-02-17</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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