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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 xOaT57LNtBJeqD5cScWYCg==

<SEC-DOCUMENT>0001164710-03-000007.txt : 20030611
<SEC-HEADER>0001164710-03-000007.hdr.sgml : 20030611
<ACCEPTANCE-DATETIME>20030611160541
ACCESSION NUMBER:		0001164710-03-000007
CONFORMED SUBMISSION TYPE:	5
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030331
FILED AS OF DATE:		20030611

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IGEN INTERNATIONAL INC /DE
		CENTRAL INDEX KEY:			0000916304
		STANDARD INDUSTRIAL CLASSIFICATION:	PATENT OWNERS & LESSORS [6794]
		IRS NUMBER:				942852543
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		16020 INDUSTRIAL DR
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877
		BUSINESS PHONE:		3019848000

	MAIL ADDRESS:	
		STREET 1:		16020 INDUSTRIAL DRIVE
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IGEN INC /CA/
		DATE OF NAME CHANGE:	19931216

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			WOHLSTADTER SAMUEL J
		CENTRAL INDEX KEY:			0001034579

	FILING VALUES:
		FORM TYPE:		5
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23252
		FILM NUMBER:		03740822

	BUSINESS ADDRESS:	
		STREET 1:		C/O IGEN INTERNATIONAL INC
		STREET 2:		16020 INDUSTRIAL ROAD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20877
		BUSINESS PHONE:		3018699800

	MAIL ADDRESS:	
		STREET 1:		C/O IGEN INTERNATIONAL, INC.
		STREET 2:		16020 INDUSTRIAL DRIVE
		CITY:			GAITHERSBURGH
		STATE:			MD
		ZIP:			20877
</SEC-HEADER>
<DOCUMENT>
<TYPE>5
<SEQUENCE>1
<FILENAME>form_5-2003ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<!-- - EDGAR Ease Plus 1.0                                   04/22/03  TZ    -->
<ownershipDocument>
    <schemaVersion>X0101</schemaVersion>

    <documentType>5</documentType>
   <periodOfReport>2003-03-31</periodOfReport>
   <notSubjectToSection16>0</notSubjectToSection16>
    <form3HoldingsReported>0</form3HoldingsReported>

    <form4TransactionsReported>0</form4TransactionsReported>

    <issuer>
        <issuerCik>0000916304</issuerCik>
        <issuerName>IGEN INTERNATIONAL INC /DE</issuerName>
        <issuerTradingSymbol>IGEN</issuerTradingSymbol>
   </issuer>
   <reportingOwner>
      <reportingOwnerId>
            <rptOwnerCik>0001034579</rptOwnerCik>
            <rptOwnerName>WOHLSTADTER SAMUEL J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>  </rptOwnerStreet1>
            <rptOwnerStreet2>  </rptOwnerStreet2>
            <rptOwnerCity>  </rptOwnerCity>
            <rptOwnerState>  </rptOwnerState>
            <rptOwnerZipCode>  </rptOwnerZipCode>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
         <isDirector>1</isDirector>
         <isOfficer>1</isOfficer>
         <isTenPercentOwner>1</isTenPercentOwner>
         <isOther>0</isOther>
         <officerTitle>Chief Executive Officer</officerTitle>
       </reportingOwnerRelationship>
   </reportingOwner>
   <derivativeSecurity>
      <securityTitle>
         <value>Option to Buy</value>
            <footnoteId id="F1"/>
      </securityTitle>
      <conversionOrExercisePrice>
         <value>37.91</value>
      </conversionOrExercisePrice>
      <transactionDate>
         <value>2002-06-04</value>
      </transactionDate>
      <transactionCoding>
         <transactionFormType>5</transactionFormType>
         <transactionCode>M</transactionCode>
         <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionAmounts>
         <transactionShares>
           <value>150000</value>
         </transactionShares>
         <transactionValue>
           <value>0</value>
         </transactionValue>
         <transactionAcquiredDisposedCode>
           <value>A</value>
         </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
         <value>2002-06-04</value>
      </exerciseDate>
      <expirationDate>
         <value>2012-06-04</value>
      </expirationDate>
      <underlyingSecurity>
         <underlyingSecurityTitle>
           <value>Common Stock</value>
         </underlyingSecurityTitle>
         <underlyingSecurityShares>
           <value>150000</value>
         </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
         <sharesOwnedFollowingTransaction>
           <value>150000</value>
         </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
         <directOrIndirectOwnership>
           <value>D</value>
         </directOrIndirectOwnership>
      </ownershipNature>
   </derivativeSecurity>
   <footnotes>
<footnote id="F1"> Option granted under the Issuer's 1994 Stock Option Plan. Option vests 20% one year from date of grant and then an additional 5% vest each quarter thereafter.</footnote>
   </footnotes>
   <ownerSignature>
      <signatureName>/s/ Samuel J. Wohlstadter</signatureName>
      <signatureDate>2003-06-11</signatureDate>
   </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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