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Note 13 - Commitments and Contingencies (Details Textual) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Operating Leases, Rent Expense $ 2,308 $ 2,362 $ 2,252
Financial Grants in Support of Research and Development, Royalty Obligation 5.00%    
Loss Contingency Accrual $ 9,388