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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (149,436) $ (96,431)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,694 1,008
Gain on sale of assets (1,948) (2,568)
Deferred rent 1,231 (208)
Cease-use expense (544) (584)
Amortization of debt issuance costs 526 0
Amortization of debt discount 6,755 0
Amortization of premiums on investments 1,202 3,151
Non-cash share-based compensation expense 29,070 20,511
Change in operating assets and liabilities:    
Accounts receivable (29,818) 0
Inventory (242) 0
Other current assets (4,315) 34
Accounts payable and accrued liabilities 11,107 878
Cease-use liability (188) (239)
Other non-current liabilities 0 (108)
Net cash used in operating activities (134,906) (74,556)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchases of investments (444,538) (217,141)
Sales and maturities of investments 257,235 318,776
Proceeds from sales of property and equipment 7 13
Deposits and restricted cash 270 (92)
Purchases of property and equipment (4,563) (3,761)
Net cash (used in) provided by investing activities (191,589) 97,795
CASH FLOWS FROM FINANCING ACTIVITIES    
Issuance of common stock 8,265 2,327
Proceeds from issuance of senior convertible notes, net 502,781  
Net cash provided by financing activities 511,046 2,327
Net increase in cash and cash equivalents 184,551 25,566
Cash and cash equivalents at beginning of the period 83,267 74,195
Cash and cash equivalents at end of the period 267,818 99,761
Supplemental Cash Flow Information    
Cash paid for interest during the period $ 0 $ 0