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Condensed Consolidated Balance Sheets (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Current assets:    
Cash and cash equivalents $ 170,262us-gaap_CashAndCashEquivalentsAtCarryingValue $ 31,014us-gaap_CashAndCashEquivalentsAtCarryingValue
Short-term investments, available for sale 199,745us-gaap_ShortTermInvestments 162,795us-gaap_ShortTermInvestments
Receivables under collaboration agreements 30,030us-gaap_ReceivablesNetCurrent  
Other current assets 4,916us-gaap_OtherAssetsCurrent 4,394us-gaap_OtherAssetsCurrent
Total current assets 404,953us-gaap_AssetsCurrent 198,203us-gaap_AssetsCurrent
Property and equipment, net 2,543us-gaap_PropertyPlantAndEquipmentNet 2,507us-gaap_PropertyPlantAndEquipmentNet
Long-term investments, available for sale 115,452us-gaap_LongTermInvestments 37,492us-gaap_LongTermInvestments
Restricted cash 4,831us-gaap_RestrictedCashAndCashEquivalentsNoncurrent 4,831us-gaap_RestrictedCashAndCashEquivalentsNoncurrent
Total assets 527,779us-gaap_Assets 243,033us-gaap_Assets
Current liabilities:    
Accounts payable 1,270us-gaap_AccountsPayableCurrent 246us-gaap_AccountsPayableCurrent
Accrued liabilities 9,938us-gaap_AccruedLiabilitiesCurrent 11,508us-gaap_AccruedLiabilitiesCurrent
Current portion of cease-use liability 479nbix_CeaseUseLiabilityCurrent 467nbix_CeaseUseLiabilityCurrent
Current portion of deferred rent 152us-gaap_DeferredRentCreditCurrent 119us-gaap_DeferredRentCreditCurrent
Current portion of deferred gain on sale of real estate 3,348nbix_DeferredGainOnSaleOfRealEstateCurrent 3,324nbix_DeferredGainOnSaleOfRealEstateCurrent
Total current liabilities 15,187us-gaap_LiabilitiesCurrent 15,664us-gaap_LiabilitiesCurrent
Deferred gain on sale of real estate 13,468nbix_DeferredGainOnSaleOfRealEstateNoncurrent 14,322nbix_DeferredGainOnSaleOfRealEstateNoncurrent
Deferred revenue 10,231us-gaap_DeferredRevenueNoncurrent 0us-gaap_DeferredRevenueNoncurrent
Deferred rent 1,817us-gaap_DeferredRentCreditNoncurrent 1,877us-gaap_DeferredRentCreditNoncurrent
Cease-use liability 2,086nbix_CeaseUseLiabilityNoncurrent 2,211nbix_CeaseUseLiabilityNoncurrent
Other liabilities 260us-gaap_OtherLiabilitiesNoncurrent 260us-gaap_OtherLiabilitiesNoncurrent
Total liabilities 43,049us-gaap_Liabilities 34,334us-gaap_Liabilities
Commitments and contingencies      
Stockholders' equity:    
Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding 0us-gaap_PreferredStockValue 0us-gaap_PreferredStockValue
Common stock, $0.001 par value; 110,000,000 shares authorized; issued and outstanding shares were 85,372,303 as of March 31, 2015 and 76,465,942 as of December 31, 2014 85us-gaap_CommonStockValue 76us-gaap_CommonStockValue
Additional paid-in capital 1,312,321us-gaap_AdditionalPaidInCapital 1,035,205us-gaap_AdditionalPaidInCapital
Accumulated other comprehensive loss (179)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax (277)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax
Accumulated deficit (827,497)us-gaap_RetainedEarningsAccumulatedDeficit (826,305)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' equity 484,730us-gaap_StockholdersEquity 208,699us-gaap_StockholdersEquity
Total liabilities and stockholders' equity $ 527,779us-gaap_LiabilitiesAndStockholdersEquity $ 243,033us-gaap_LiabilitiesAndStockholdersEquity