CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013
Revenues:
License fees	$ 0	$ 730
Total revenues	0	730
Operating expenses:
Research and development	8,572	10,313
General and administrative	4,153	3,392
Total operating expenses	12,725	13,705
Loss from operations	(12,725)	(12,975)
Other income:
(Loss) gain on sale/disposal of assets	(10)	13
Deferred gain on real estate	804	782
Investment income, net	89	103
Other income, net	0	2
Total other income	883	900
Net loss	(11,842)	(12,075)
Net loss per common share:
Basic and diluted	$ (0.17)	$ (0.18)
Shares used in the calculation of net loss per common share:
Basic and diluted	70,260	66,600
Other comprehensive loss:
Net loss	(11,842)	(12,075)
Net unrealized losses on available-for-sale securities	(199)	(42)
Comprehensive loss	$ (12,041)	$ (12,117)