STOCKHOLDERS' EQUITY AND SHARE-BASED COMPENSATION EXPENSE Share-based Compensation Expense (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended
	Mar. 31, 2015	Mar. 31, 2014
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 4,063	$ 3,145
Costs of product sales [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	695	537
Research and development [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	514	507
Selling, general and administrative [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 2,854	$ 2,101