STOCKHOLDERS' EQUITY AND SHARE-BASED COMPENSATION EXPENSE, Stock Plans and Share-Based Compensation (Details) (USD $) Share data in Millions, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Common stock reserved for future issuance (in shares)	5.6		5.6
Common Stock, Capital Shares Reserved for Future Issuance 2012 Inducement	2.0		2.0
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 1,999,000	$ 2,259,000	$ 5,109,000	$ 14,857,000
Unrecognized share-based compensation expense	10,900,000		10,900,000
Weighted-average term of unrecognized share-based compensation expense, Stock Options			2 years 7 months 17 days
Weighted-average term of unrecognized share-based compensation expense, Restricted Stock			2 years 2 months 15 days
Costs of product sales [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	223,000	403,000	651,000	1,114,000
Research and development [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	340,000	307,000	906,000	980,000
Selling, general and administrative [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 1,436,000	$ 1,549,000	$ 3,552,000	$ 12,763,000