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STOCKHOLDERS' EQUITY AND SHARE-BASED COMPENSATION EXPENSE (Tables)
9 Months Ended
Sep. 30, 2013
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Share-based compensation expense
The Company recognized share-based compensation expense as follows (in thousands):

 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2013
 
2012
 
2013
 
2012
Costs of product sales
$
223

 
$
403

 
$
651

 
$
1,114

Research and development
340

 
307

 
906

 
980

Selling, general and administrative
1,436

 
1,549

 
3,552

 
12,763

Total share-based compensation expense
$
1,999

 
$
2,259

 
$
5,109

 
$
14,857

Fair value of options estimated at the date of grant with weighted-average assumptions
The fair value of options was estimated at the date of grant using the Black Scholes Merton option pricing model with the following weighted‑average assumptions:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2013
 
2012
 
2013
 
2012
Risk free interest rate
1.4
%
 
0.6
%
 
1.0
%
 
0.6
%
Expected dividend yield
0.0
%
 
0.0
%
 
0.0
%
 
0.0
%
Expected volatility
68
%
 
67
%
 
68
%
 
67
%
Expected option term (in years)
4.6

 
4.6

 
4.6

 
4.6

Assumptions Used to Value Employees Stock Purchase Rights
During the three and nine months ended September 30, 2013 and 2012, the fair value of shares under the ESPP was estimated using the following assumptions:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2013
 
2012
 
2013
 
2012
Risk free interest rate
0.1
%
 
0.1
%
 
0.1
%
 
0.1
%
Expected dividend yield
0.0
%
 
0.0
%
 
0.0
%
 
0.0
%
Expected volatility
52.6
%
 
67
%
 
52.6
%
 
67
%
Expected term (in years)
0.6

 
0.8

 
0.6

 
0.8