CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
REVENUE:
Product sales	$ 266,063	$ 241,273	$ 277,743
Services and Other	29,560	26,201	33,003
Total revenue	295,623	267,474	310,746
COSTS AND EXPENSES:
Cost of product sales	116,261	97,815	117,384
Cost of services and other	15,874	13,137	15,822
Research and development	57,881	63,591	67,934
Selling, general and administrative	142,853	109,572	114,773
Restructuring charges	1,845	0	0
Total costs and expenses	334,714	284,115	315,913
Loss from operations	(39,091)	(16,641)	(5,167)
Interest income and other, net	(265)	(6,302)	(1,487)
Interest expense	7,193	3,813	7,706
Gain from repurchase of convertible notes	0	0	6,297
Loss before income taxes	(46,549)	(26,756)	(8,063)
Income tax (benefit) provision	(35,853)	1,405	2,170
Net loss	$ (10,696)	$ (28,161)	$ (10,233)
Basic and diluted net loss per common share (in dollars per share)	$ (0.15)	$ (0.4)	$ (0.15)
Shares used in computing basic and diluted net loss per common share (in shares)	70,300	70,877	68,856