CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) (USD $) In Thousands, except Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
REVENUE:
Product sales	$ 58,144	$ 65,103	$ 125,607	$ 138,546
Services	5,259	4,742	9,767	9,205
Royalties and other revenue	1,256	1,833	3,009	4,114
Total revenue	64,659	71,678	138,383	151,865
COSTS AND EXPENSES:
Cost of product sales	22,367	27,535	46,266	55,994
Cost of services and other	3,426	3,554	6,626	8,143
Research and development	15,298	17,815	31,566	36,294
Selling, general and administrative	26,675	28,428	53,887	59,807
Total costs and expenses	67,766	77,332	138,345	160,238
(Loss) income from operations	(3,107)	(5,654)	38	(8,373)
Interest income and other, net	499	738	(1,395)	(2,860)
Interest expense	937	2,340	1,875	4,772
Gain from repurchase of convertible notes	0	1,744	0	1,744
Loss before income taxes	(3,545)	(5,512)	(3,232)	(14,261)
Income tax provision	127	29	401	900
Net loss	$ (3,672)	$ (5,541)	$ (3,633)	$ (15,161)
Basic and diluted net loss per common share	$ (0.05)	$ (0.08)	$ (0.05)	$ (0.22)
Shares used in computing basic and diluted net loss per common share	69,504	69,030	70,700	68,981