Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Revenues
Royalty revenue	$ 2,132		$ 5,028
Collaboration and license revenue	3,296	88	4,990	193
Other revenue		96	56	292
Total revenue	5,428	184	10,074	485
Operating expenses
Research and development	11,373	4,376	26,793	12,197
General and administrative	4,244	2,627	11,051	5,906
Total operating expenses	15,617	7,003	37,844	18,103
Loss from operations	(10,189)	(6,819)	(27,770)	(17,618)
Other income (expense), net		16		(183)
Interest income (expense), net	7	(20)	12	(27)
Net loss	$ (10,182)	$ (6,823)	$ (27,758)	$ (17,828)
Basic and diluted net loss per share	$ (0.43)	$ (92.21)	$ (1.26)	$ (143.77)
Weighted average shares used in basic and diluted per share computations	23,825	74	21,984	124