Share Based Payments (Tables)

9 Months Ended

Sep. 30, 2012

Share Based Payments [Abstract]

Summary of stock option activity under all equity plans

A summary of stock option activity under all equity plans for the three and nine months ended September 30, 2012 is as follows:

	Number of Shares			Weighted Average Exercise Price
Outstanding at December 31, 2011		2,371		$	15.34
Options granted		26			32.90
Options exercised		(82	)		3.48
Options canceled or expired		(11	)		16.03
Outstanding at March 31, 2012		2,304		$	15.96
Options granted		616			40.74
Options exercised		(136	)		1.27
Options canceled or expired		(34	)		112.92
Outstanding at June 30, 2012		2,750		$	21.03
Options granted		—			—
Options exercised		(123	)		3.84
Options canceled or expired		(34	)		22.72
Outstanding at September 30, 2012		2,593		$	21.82

Recognized stock-based compensation expense on all stock option awards

The Company recognized stock-based compensation expense on all stock option awards for the three and nine months ended September 30, 2012 and 2011, as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2012		2011		2012		2011
Research and development	$	495	$	35	$	926	$	94
General and administrative		1,060		101		2,141		198
	$	1,555	$	136	$	3,067	$	292