EXHIBIT 99.1

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that this Statement on Schedule 13D relating to the common stock, $0.001 par value, of Synageva BioPharma Corp. is being filed with the Securities and Exchange Commission on behalf of each of them.

January 9, 2013

BAKER BROS. ADVISORS, LLC
By:	/s/ Scott L. Lessing
	Name: Scott L. Lessing
	Title:  President
By:	/s/ Julian C. Baker
	Julian C. Baker
By:	/s/ Felix J. Baker
	Felix J. Baker
FBB Associates
By:	/s/ Julian C. Baker
	Name: Julian C. Baker
	Title: Partner