Acquisitions (Assets and Liabilities Assumed) (Details) - USD ($) $ in Thousands	Dec. 01, 2021	Nov. 01, 2021	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Intangible assets:
Goodwill			$ 345,588	$ 161,765	$ 223,176
Oqton, Inc.
Business Acquisition [Line Items]
Current assets, including cash acquired of $3,454		$ 4,462
Intangible assets:
Total intangible assets		18,000
Goodwill		167,576
Other assets		855
Net assets acquired		188,168
Liabilities:
Accounts payable and accrued liabilities		2,235
Total liabilities		2,725
Deferred revenue		490
Net assets acquired		188,168
Cash acquired		3,454
Oqton, Inc. | Product technology
Intangible assets:
Total intangible assets		11,200
Oqton, Inc. | Trade names
Intangible assets:
Total intangible assets		$ 6,800
Volumetric Biotechnologies, Inc.
Business Acquisition [Line Items]
Current assets, including cash acquired of $3,454	$ 3,143
Intangible assets:
Total intangible assets	639
Goodwill	38,620
Other assets	1,194
Net assets acquired	40,172
Liabilities:
Accounts payable and accrued liabilities	3,424
Total liabilities	3,424
Net assets acquired	40,172
Cash acquired	389
Volumetric Biotechnologies, Inc. | Patent costs
Intangible assets:
Total intangible assets	$ 639