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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AGIOS PHARMACEUTICALS INC COM 00847X104   243,822,126 5,654,502 SH   OTR   5,654,502 0 0
AIRBNB INC COM CL A 009066101   257,922,630 1,701,000 SH   OTR   1,701,000 0 0
ALPHABET INC CAP STK CL C 02079K107   329,521,367 1,796,540 SH   OTR   1,796,540 0 0
ALTIMMUNE INC COM NEW 02155H200   183,540 27,600 SH   OTR   27,600 0 0
AMGEN INC COM 031162100   72,488,400 232,000 SH   OTR   232,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109   158,720 16,000 SH   OTR   16,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   2,185,420 1,150,221 SH   OTR   1,150,221 0 0
ANALOG DEVICES INC COM 032654105   293,268,448 1,284,800 SH   OTR   1,284,800 0 0
AON PLC SHS CL A G0403H108   550,521,216 1,875,200 SH   OTR   1,875,200 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   230,160 6,000 SH   OTR   6,000 0 0
ARAMARK COM 03852U106   575,932,643 16,929,237 SH   OTR   16,929,237 0 0
ARCELLX INC COMMON STOCK 03940C100   220,760 4,000 SH   OTR   4,000 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   241,800 26,000 SH   OTR   26,000 0 0
ARDELYX INC COM 039697107   170,430 23,000 SH   OTR   23,000 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   2,292,000 200,000 SH   OTR   200,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   187,933,907 2,409,718 SH   OTR   2,409,718 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   204,250 5,000 SH   OTR   5,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104   322,000 4,000 SH   OTR   4,000 0 0
BEAM THERAPEUTICS INC COM 07373V105   185,404,472 7,913,123 SH   OTR   7,913,123 0 0
BERENSON ACQUISITION CORP I CL A COM 083690107   3,042,865 285,715 SH   OTR   285,715 0 0
BEYOND MEAT INC COM 08862E109   127,490 19,000 SH   OTR   19,000 0 0
BIODESIX INC COM 09075X108   2,873,608 1,878,175 SH   OTR   1,878,175 0 0
BIOHAVEN LTD COM G1110E107   78,028,080 2,248,000 SH   OTR   2,248,000 0 0
BLOCKCHAIN COINVSTRS ACQ CRP *W EXP 11/01/202 G11765115   8,985 150,000 SH   OTR   150,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   431,120 4,000 SH   OTR   4,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107   316,446,181 4,109,157 SH   OTR   4,109,157 0 0
BRIGHTSPRING HEALTH SVCS INC COM 10950A106   249,920 22,000 SH   OTR   22,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107   129,360 28,000 SH   OTR   28,000 0 0
CANOPY GROWTH CORP COM NEW 138035704   193,500 30,000 SH   OTR   30,000 0 0
CARA THERAPEUTICS INC COM 140755109   401,513 1,556,251 SH   OTR   1,556,251 0 0
CARTICA ACQUISITION CORP *W EXP 04/30/202 G1995D117   33,933 175,000 SH   OTR   175,000 0 0
CBRE GROUP INC CL A 12504L109   336,212,030 3,773,000 SH   OTR   3,773,000 0 0
CENCORA INC COM 03073E105   54,702,840 242,800 SH   OTR   242,800 0 0
CENTENE CORP DEL COM 15135B101   143,750,003 2,168,175 SH   OTR   2,168,175 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   18,023,880 1,996,000 SH   OTR   1,996,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   48,659,100 1,190,000 SH   OTR   1,190,000 0 0
CHEMED CORP NEW COM 16359R103   217,032 400 SH   OTR   400 0 0
CHURCHILL CAPITAL CORP VII *W EXP 02/29/202 17144M110   70,000 200,000 SH   OTR   200,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201   3,584,107 425,161 SH   OTR   425,161 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   22,260,630 497,000 SH   OTR   497,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   28,625,300 530,000 SH   OTR   530,000 0 0
CYTOKINETICS INC COM NEW 23282W605   5,548,032 102,400 SH   OTR   102,400 0 0
DISNEY WALT CO COM 254687106   355,673,461 3,582,168 SH   OTR   3,582,168 0 0
DYNE THERAPEUTICS INC COM 26818M108   211,740 6,000 SH   OTR   6,000 0 0
ELEVATION ONCOLOGY INC COM 28623U101   9,715,729 3,598,418 SH   OTR   3,598,418 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106   27,172,150 2,095,000 SH   OTR   2,095,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100   257,370 3,000 SH   OTR   3,000 0 0
EXELIXIS INC COM 30161Q104   608,993,175 27,102,500 SH   OTR   27,102,500 0 0
FLUTTER ENTMT PLC SHS G3643J108   36,617,888 200,800 SH   OTR 1 200,800 0 0
FORTE BIOSCIENCES INC COM 34962G109   972,214 1,810,455 SH   OTR   1,810,455 0 0
FULL TRUCK ALLIANCE CO LTD SPONSORED ADS 35969L108   207,836,436 25,850,303 SH   OTR   25,850,303 0 0
GDS HLDGS LTD SPONSORED ADS 36165L108   11,390,776 1,226,133 SH   OTR   1,226,133 0 0
GERON CORP COM 374163103   71,388,880 16,837,000 SH   OTR   16,837,000 0 0
GLAUKOS CORP COM 377322102   307,710 2,600 SH   OTR   2,600 0 0
GLOBUS MED INC CL A 379577208   246,564 3,600 SH   OTR   3,600 0 0
GORES HOLDINGS IX INC *W EXP 01/14/202 38287A119   17,908 166,664 SH   OTR   166,664 0 0
GRIFOLS S A SP ADR REP B NVT 398438408   176,540 28,000 SH   OTR   28,000 0 0
GRINDR INC *W EXP 11/18/202 39854F119   1,755,000 540,000 SH   OTR   540,000 0 0
HCA HEALTHCARE INC COM 40412C101   321,280 1,000 SH   OTR   1,000 0 0
HEALTHEQUITY INC COM 42226A107   241,360 2,800 SH   OTR   2,800 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   6,132,000 600,000 SH   OTR   600,000 0 0
HIMS & HERS HEALTH INC COM CL A 433000106   201,900 10,000 SH   OTR   10,000 0 0
HOLDCO NUVO GROUP D G LTD *W EXP 05/01/202 M53051112   4,260 200,000 SH   OTR   200,000 0 0
HOWMET AEROSPACE INC COM 443201108   197,322,962 2,541,839 SH   OTR   2,541,839 0 0
HUMANA INC COM 444859102   224,190 600 SH   OTR   600 0 0
ICON PLC SHS G4705A100   55,860,354 178,200 SH   OTR   178,200 0 0
IMMUNOVANT INC COM 45258J102   316,800 12,000 SH   OTR   12,000 0 0
INSMED INC COM PAR $.01 457669307   38,056,000 568,000 SH   OTR   568,000 0 0
INTUIT COM 461202103   413,448,839 629,097 SH   OTR   629,097 0 0
INTUITIVE MACHINES INC *W EXP 99/99/999 46125A118   298,533 440,965 SH   OTR   440,965 0 0
IONIS PHARMACEUTICALS INC COM 462222100   228,768 4,800 SH   OTR   4,800 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   208,520 26,000 SH   OTR   26,000 0 0
IQIYI INC NOTE 4.000%12/1 46267XAE8   162,080,625 163,100,000 PRN   OTR   163,100,000 0 0
IQVIA HLDGS INC COM 46266C105   618,045,886 2,923,032 SH   OTR   2,923,032 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108   84,760 13,000 SH   OTR   13,000 0 0
ISHARES TR ISHARES BIOTECH 464287556   480,410,000 3,500,000 SH Put OTR   3,500,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   862,282,500 4,250,000 SH Put OTR   4,250,000 0 0
JAWS MUSTANG ACQUISITION COR *W EXP 01/30/202 G50737124   21,500 200,000 SH   OTR   200,000 0 0
KE HLDGS INC SPONSORED ADS 482497104   67,082,787 4,740,833 SH   OTR   4,740,833 0 0
KENSINGTON CAPITAL ACQUISITI *W EXP 99/99/999 G5251K129   15,058 581,400 SH   OTR   581,400 0 0
KRYSTAL BIOTECH INC COM 501147102   367,280 2,000 SH   OTR   2,000 0 0
LANTHEUS HLDGS INC COM 516544103   182,999,136 2,279,227 SH   OTR   2,279,227 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   24,660,000 2,055,000 SH   OTR   2,055,000 0 0
LONGBOARD PHARMACEUTICALS IN COM 54300N103   79,481,715 2,940,500 SH   OTR   2,940,500 0 0
LUFAX HOLDING LTD SPONSORED ADR 54975P201   35,550 15,000 SH   OTR   15,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   929,851 3,319 SH   OTR   3,319 0 0
MARBLEGATE ACQUISITION CORP COM CL A 56608A105   1,621,500 150,000 SH   OTR   150,000 0 0
MARBLEGATE ACQUISITION CORP *W EXP 08/31/202 56608A113   55,094 1,485,000 SH   OTR   1,485,000 0 0
MASIMO CORP COM 574795100   140,997,764 1,119,563 SH   OTR   1,119,563 0 0
MASTERCARD INCORPORATED CL A 57636Q104   204,156,054 462,771 SH   OTR   462,771 0 0
MERIT MED SYS INC COM 589889104   257,850 3,000 SH   OTR   3,000 0 0
MERUS N V COM N5749R100   236,680 4,000 SH   OTR   4,000 0 0
METAGENOMI INC COM 59102M104   5,480,260 1,343,201 SH   OTR   1,343,201 0 0
METALS ACQUISITION LIMITED ORD SHS G60409110   5,615,597 410,197 SH   OTR   410,197 0 0
MICROSOFT CORP COM 594918104   537,581,627 1,202,778 SH   OTR   1,202,778 0 0
MODERNA INC COM 60770K107   154,375,000 1,300,000 SH Put OTR   1,300,000 0 0
NASDAQ INC COM 631103108   452,354,887 7,506,719 SH   OTR   7,506,719 0 0
NATERA INC COM 632307104   483,033,718 4,460,557 SH   OTR   4,460,557 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581206   114,231,231 1,469,590 SH   OTR   1,469,590 0 0
NEW YORK TIMES CO CL A 650111107   507,995,006 9,919,840 SH   OTR   9,919,840 0 0
NOVAVAX INC COM NEW 670002401   4,775,985 377,250 SH   OTR   377,250 0 0
NURIX THERAPEUTICS INC COM 67080M103   2,270,635 108,799 SH   OTR   108,799 0 0
NVNI GROUP LIMITED *W EXP 11/01/202 G50716110   8,869 375,000 SH   OTR   375,000 0 0
OSCAR HEALTH INC CL A 687793109   174,020 11,000 SH   OTR   11,000 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   184,950 135,000 SH   OTR   135,000 0 0
PERCEPTION CAPITAL CORP IV *W EXP 99/99/999 G7330C110   16,440 300,000 SH   OTR   300,000 0 0
PG&E CORP COM 69331C108   12,087,960 692,323 SH   OTR   692,323 0 0
PRIME MEDICINE INC COM 74168J101   3,855,000 750,000 SH   OTR   750,000 0 0
PROGYNY INC COM 74340E103   37,436,185 1,308,500 SH   OTR   1,308,500 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   202,382,784 5,840,773 SH   OTR   5,840,773 0 0
QUANTERIX CORP COM 74766Q101   1,056,800 80,000 SH   OTR   80,000 0 0
R1 RCM INC COM 77634L105   200,960 16,000 SH   OTR   16,000 0 0
REVOLUTION MEDICINES INC COM 76155X100   378,696,027 9,757,692 SH   OTR   9,757,692 0 0
REVOLUTION MEDICINES INC *W EXP 12/17/202 76155X118   8,562 120,085 SH   OTR   120,085 0 0
RIGETTI COMPUTING INC *W EXP 99/99/999 76655K111   3,122 22,675 SH   OTR   22,675 0 0
RIO TINTO PLC SPONSORED ADR 767204100   9,065,375 137,500 SH   OTR 1 137,500 0 0
ROIVANT SCIENCES LTD SHS G76279101   7,113,610 673,000 SH   OTR   673,000 0 0
S&P GLOBAL INC COM 78409V104   348,742,564 781,934 SH   OTR   781,934 0 0
SABRA HEALTH CARE REIT INC COM 78573L106   215,600 14,000 SH   OTR   14,000 0 0
SAGE THERAPEUTICS INC COM 78667J108   464,808 42,800 SH   OTR   42,800 0 0
SALESFORCE INC COM 79466L302   757,632,050 2,946,838 SH   OTR   2,946,838 0 0
SAREPTA THERAPEUTICS INC COM 803607100   21,061,400 133,300 SH Call OTR   133,300 0 0
SAREPTA THERAPEUTICS INC COM 803607100   362,610,000 2,295,000 SH   OTR   2,295,000 0 0
SAVARA INC COM 805111101   18,376,800 4,560,000 SH   OTR   4,560,000 0 0
SDCL EDGE ACQUISITION CORP *W EXP 99/99/999 G79471127   190,575 866,250 SH   OTR   866,250 0 0
SEP ACQUISITION CORP *W EXP 99/99/999 589381110   6,410 866,250 SH   OTR   866,250 0 0
SERVICENOW INC COM 81762P102   357,187,514 454,050 SH   OTR   454,050 0 0
SHERWIN WILLIAMS CO COM 824348106   193,248,347 647,550 SH   OTR   647,550 0 0
SILICON MOTION TECHNOLOGY CO SPONSORED ADR 82706C108   45,964,579 567,534 SH   OTR   567,534 0 0
SLAM CORP *W EXP 99/99/999 G8210L121   4,386 17,627 SH   OTR   17,627 0 0
SOLID POWER INC *W EXP 12/08/202 83422N113   64,648 405,316 SH   OTR   405,316 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   4,843,558,000 8,900,000 SH Put OTR   8,900,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   15,657,660 666,000 SH   OTR   666,000 0 0
SUMMIT MIDSTREAM PARTNERS LP COM UNIT LTD 866142409   2,070,090 58,214 SH   OTR   58,214 0 0
SUNRUN INC NOTE 2/0 86771WAB1   112,447,383 129,146,000 PRN   OTR   129,146,000 0 0
SWIFTMERGE ACQUISITION CORP *W EXP 12/13/202 G63836111   79,200 990,000 SH   OTR   990,000 0 0
SWIFTMERGE ACQUISITION CORP CLASS A ORD SHS G63836103   3,277,500 300,000 SH   OTR   300,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   205,300 10,000 SH   OTR   10,000 0 0
TAL EDUCATION GROUP SPONSORED ADS 874080104   14,564,550 1,365,000 SH   OTR   1,365,000 0 0
TECTONIC THERAPEUTIC INC COM 878972108   7,098,735 431,010 SH   OTR   431,010 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   91,450,409 687,442 SH   OTR   687,442 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   408,753,268 739,156 SH   OTR   739,156 0 0
TRANSMEDICS GROUP INC COM 89377M109   301,240 2,000 SH   OTR   2,000 0 0
TRANSUNION COM 89400J107   447,564,425 6,035,119 SH   OTR   6,035,119 0 0
TWIST BIOSCIENCE CORP COM 90184D100   9,461,760 192,000 SH   OTR   192,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   4,068,900 99,000 SH   OTR   99,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   45,552,650 143,000 SH   OTR   143,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102   824,084,532 1,618,200 SH   OTR   1,618,200 0 0
VAXCYTE INC COM 92243G108   21,897,900 290,000 SH   OTR   290,000 0 0
VEEVA SYS INC CL A COM 922475108   662,862 3,622 SH   OTR   3,622 0 0
VENTYX BIOSCIENCES INC COM 92332V107   7,322,700 3,170,000 SH   OTR   3,170,000 0 0
VISA INC COM CL A 92826C839   215,720,418 821,886 SH   OTR   821,886 0 0
VNET GROUP INC SPONSORED ADS A 90138A103   1,361,750 650,000 SH   OTR   650,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   18,129,720 2,292,000 SH   OTR   2,292,000 0 0
WABTEC COM 929740108   346,050,159 2,189,498 SH   OTR   2,189,498 0 0
ZTO EXPRESS CAYMAN INC NOTE 1.500% 9/0 98980AAB1   72,922,560 75,000,000 PRN   OTR   75,000,000 0 0
ZYMEWORKS INC COM 98985Y108   13,624,510 1,601,000 SH   OTR   1,601,000 0 0