SCHEDULE OF CONVERTIBLE DEBENTURES AND NOTES, NET OF DISCOUNT (Details) - USD ($)	Mar. 31, 2023	Dec. 31, 2022
Short-Term Debt [Line Items]
Other debt	$ 590,050	$ 390,050
Accrued interest	38,828
Total of debentures, notes and other debt	11,860,228	11,256,971
Bridge Investor [Member]
Short-Term Debt [Line Items]
Other debt	245,000	245,000
5% Convertible Note Payable - Stephen Boesch [Member]
Short-Term Debt [Line Items]
Convertible note payable	125,208	123,958
5% Convertible Note Payable - Related Party [Member]
Short-Term Debt [Line Items]
Convertible note payable	291,858	288,733
5% Convertible Note Payable - Sanjay Jha [Member]
Short-Term Debt [Line Items]
Convertible note payable	291,378	288,253
Five Percent Convertible Note Payable CEO CTO and CFO Related Parties [Member]
Short-Term Debt [Line Items]
Convertible note payable	95,483	94,457
5% Convertible note payable - Bridge Investors [Member]
Short-Term Debt [Line Items]
Convertible note payable	195,622	193,522
5% Convertible Note Payable [Member]
Short-Term Debt [Line Items]
Convertible note payable	999,549	988,923
5% Convertible note – Autotelic Inc– Related Party [Member] | August 2021 Convertible Notes [Member]
Short-Term Debt [Line Items]
Convertible note payable	270,677	267,553
5% Convertible Note - Bridge Investors [Member] | August 2021 Convertible Notes [Member]
Short-Term Debt [Line Items]
Convertible note payable	404,392	399,722
5% Convertible note – CFO – Related Party [Member] | August 2021 Convertible Notes [Member]
Short-Term Debt [Line Items]
Convertible note payable	81,204	80,266
5% Convertible Note [Member] | August 2021 Convertible Notes [Member]
Short-Term Debt [Line Items]
Convertible note payable	756,273	747,541
Chief Financial Officer [Member]
Short-Term Debt [Line Items]
Other debt	25,050	25,050
Sixteen Percent Convertible Note [Member]
Short-Term Debt [Line Items]
Convertible note payable	627,550	619,345
Debt Clinical Trials GMP Convertible Note [Member]
Short-Term Debt [Line Items]
Convertible note payable	4,682,193	4,659,782
Sixteen Percent Convertible Note Accredited Investors [Member]
Short-Term Debt [Line Items]
Convertible note payable	1,191,377	885,312
Autotelic [Member]
Short-Term Debt [Line Items]
Other debt	320,000	120,000
10% Convertible Note Payable Due April 23, 2022 [Member] | Related Party [Member]
Short-Term Debt [Line Items]
Convertible note payable	164,444	164,444
10% Convertible Note Payable Due April 23, 2022 [Member] | Bridge Investor [Member]
Short-Term Debt [Line Items]
Convertible note payable	35,556	35,556
10% Convertible Note Payable Due August 6, 2022 [Member] | Bridge Investor [Member]
Short-Term Debt [Line Items]
Convertible note payable	200,000	200,000
10% Convertible Note Payable [Member]
Short-Term Debt [Line Items]
Convertible note payable	400,000	400,000
16% Convertible Notes [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	2,574,408	2,566,018
16% Convertible Notes [Member] | Non-related Parties [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	2,449,408	2,441,471
16% Convertible Notes [Member] | Chief Financial Officer [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	$ 125,000	$ 124,547