SCHEDULE OF CONVERTIBLE NOTES, NET OF DISCOUNT (Details) - USD ($)	Mar. 31, 2022	Dec. 31, 2021
Short-Term Debt [Line Items]
Other debt	$ 294,647
Accrued Interest on Loans	4,597
Total of debentures, notes and other debt	9,769,653
Total	718,498	$ 714,288
Bridge Investor [Member]
Short-Term Debt [Line Items]
Other debt	245,000
5% Convertible Note Payable - Stephen Boesch [Member]
Short-Term Debt [Line Items]
Convertible note payable	120,208
5% Convertible Note Payable Related Party [Member]
Short-Term Debt [Line Items]
Convertible note payable	279,358
5% Convertible Note Payable - Sanjay Jha [Member]
Short-Term Debt [Line Items]
Convertible note payable	278,878
5% Convertible Note Payable - CEO, CTO and CFO [Member]
Short-Term Debt [Line Items]
Convertible note payable	91,382
5% Convertible note payable - Bridge Investors [Member]
Short-Term Debt [Line Items]
Convertible note payable	187,222
5% Convertible Note Payable [Member]
Short-Term Debt [Line Items]
Convertible note payable	957,048
5% Convertible Note Autotelic Inc [Member]
Short-Term Debt [Line Items]
Convertible note payable	257,158
5% Convertible Note Bridge Investors [Member]
Short-Term Debt [Line Items]
Convertible note payable	384,193
5% Convertible Notes Chief Financial Officer [Member]
Short-Term Debt [Line Items]
Convertible note payable	77,147
5% Convertible Note [Member]
Short-Term Debt [Line Items]
Convertible note payable	718,498
Chief Financial Officer [Member]
Short-Term Debt [Line Items]
Other debt	25,050
12% Convertible Note [Member]
Short-Term Debt [Line Items]
Convertible note payable	386,459
Debt Clinical Trials GMP Convertible Note [Member]
Short-Term Debt [Line Items]
Convertible note payable	4,591,973
Autotelic [Member]
Short-Term Debt [Line Items]
Other debt	20,000
Autotelic Related Party Convertible Note, 5% Coupon August 2022 [Member]
Short-Term Debt [Line Items]
Total	257,158	256,634
CFO Related Party Convertible Note, 5% Coupon August 2022 [Member]
Short-Term Debt [Line Items]
Total	77,147	76,531
Accredited Investors Convertible Note, 5% Coupon August 2022 [Member]
Short-Term Debt [Line Items]
Total	384,193	$ 381,123
10% Convertible Note Payable Due April 23, 2022 [Member] | Related Party [Member]
Short-Term Debt [Line Items]
Convertible note payable	159,571
10% Convertible Note Payable Due April 23, 2022 [Member] | Bridge Investor [Member]
Short-Term Debt [Line Items]
Convertible note payable	34,459
10% Convertible Note Payable Due August 6, 2022 [Member] | Bridge Investor [Member]
Short-Term Debt [Line Items]
Convertible note payable	193,325
10% Convertible Note Payable [Member]
Short-Term Debt [Line Items]
Convertible note payable	387,355
16% Convertible Notes [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	2,433,673
16% Convertible Notes [Member] | Non-related Parties [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	2,312,023
16% Convertible Notes [Member] | Chief Financial Officer [Member] | JH Darbie PPM Debt [Member]
Short-Term Debt [Line Items]
Convertible note payable	$ 121,650