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DESCRIPTION OF BUSINESS AND BASIS OF PRESENTATION (Details Narrative) - USD ($)
1 Months Ended 9 Months Ended 12 Months Ended
Feb. 25, 2020
Dec. 31, 2021
Nov. 30, 2021
Sep. 30, 2021
Aug. 31, 2021
Jun. 30, 2021
May 31, 2021
Mar. 31, 2021
Jul. 31, 2020
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Oct. 31, 2021
Jun. 30, 2020
Product Information [Line Items]                            
Common stock, shares authorized   750,000,000                 750,000,000 150,000,000    
Number of shares issued and sold                     3,435,000      
Debt instrument, convertible, conversion price   $ 0.07                 $ 0.07      
Warrants to purchase common stock   53,314,424                 53,314,424      
Stock issued during period                     $ 420,302      
Warrants issuance cost                     $ 2,023,552      
Common Stock, Par or Stated Value Per Share   $ 0.01       $ 0.20         $ 0.01 $ 0.01    
Proceeds from Issuance of Common Stock                     $ 420,293    
Convertible Debt   $ 1,000,000                 1,000,000      
Debt Instrument, Face Amount   $ 250,000 $ 250,000               $ 250,000      
Debt instrument, interest rate, stated percentage   12.00%                 12.00%      
Equity method ownership corporate joint venture ercentage   35.00%                 35.00%      
Proceeds from Convertible Debt   $ 1,250,000 $ 1,250,000               $ 307,500    
Convertible preferred stock, par value   $ 0.01 $ 0.01               $ 0.01 $ 0.01    
Net Income (Loss) Attributable to Parent                     $ (9,391,042) $ (9,502,602)    
Working capital deficit   $ 14,800,000                 14,800,000      
Business Combination, Contingent Consideration, Liability   $ 2,600,000                 2,600,000      
Net Cash Provided by (Used in) Operating Activities                     4,434,465 2,812,001    
Proceeds from Issuance of Private Placement                     $ 1,545,052 2,929,056    
Warrant term   1 year 11 months 19 days                 1 year 11 months 19 days      
Service revenue                     1,740,855    
Investor [Member]                            
Product Information [Line Items]                            
Stock issued during period           $ 10,000                
Investor [Member]                            
Product Information [Line Items]                            
Debt Instrument, Maturity Date           Mar. 31, 2022                
Bridge Financiers [Member]                            
Product Information [Line Items]                            
Proceeds from Issuance of Private Placement                     700,000      
Autotelic Inc [Member]                            
Product Information [Line Items]                            
Proceeds from Issuance of Private Placement                     $ 300,000      
Warrant [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock               100,000 100,000 100,000        
Oncotelic Warrant [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock           20,000,000.0                
Oncotelic Warrant [Member] | Investor [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock           200,000                
Edgepoint Common Stock [Member] | Warrant [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock   50,000           50,000 50,000 50,000 50,000      
Warrant exercise price per share   $ 1.00           $ 1.00 $ 1.00 $ 1.00 $ 1.00      
Edgepoint Common Stock [Member] | Oncotelic Warrant [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock           50,000   50,000 50,000 50,000        
Warrant exercise price per share   0.20                 0.20      
Warrants and Rights Outstanding           $ 10,000                
Mateon Common Stock [Member] | Warrant [Member]                            
Product Information [Line Items]                            
Warrant exercise price per share   $ 0.20                 $ 0.20      
Warrant term   3 years                 3 years      
Convertible Promissory Note [Member] | Edgepoint Common Stock [Member]                            
Product Information [Line Items]                            
Debt instrument, convertible, conversion price               $ 1.00 $ 1.00 $ 1.00        
Convertible Promissory Note [Member] | Edgepoint Common Stock [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Conversion of debt, shares               25,000 25,000          
Convertible Promissory Note [Member] | Mateon Common Stock [Member]                            
Product Information [Line Items]                            
Debt instrument, convertible, conversion price               $ 0.18 $ 0.18 $ 0.18        
One Convertible Promissory Note [Member] | Edgepoint Common Stock [Member]                            
Product Information [Line Items]                            
Debt instrument, convertible, conversion price   $ 0.18                 $ 0.18      
One Convertible Promissory Note [Member] | Edgepoint Common Stock [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Conversion of debt, shares                     138,889      
One Convertible Promissory Note [Member] | Mateon Common Stock [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Conversion of debt, shares               138,889 138,889          
2015 Equity Incentive Plan [Member]                            
Product Information [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Shares Issued in Period                     20,000,000      
Common Stock, Capital Shares Reserved for Future Issuance   27,250,000                 27,250,000      
2015 Equity Incentive Plan [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Share-based Compensation Arrangement by Share-based Payment Award, Shares Issued in Period                     20,000,000      
Paycheck Protection Plan [Member]                            
Product Information [Line Items]                            
Proceeds from Issuance of Private Placement                     $ 100,000      
Golden Mountain Partners LLC [Member]                            
Product Information [Line Items]                            
Proceeds from Convertible Debt         $ 1,500,000                  
Edgepoint AI, Inc [Member]                            
Product Information [Line Items]                            
Stock issued during period           $ 50,000                
Common Stock, Par or Stated Value Per Share           $ 1.00                
JH Darbie & Co Inc [Member]                            
Product Information [Line Items]                            
Number of shares issued and sold                     10      
Warrants and Rights Outstanding           $ 2,190,127   $ 467,637   $ 467,637        
Proceeds from Convertible Debt                     $ 1,250,000      
Proceeds from Issuance of Private Placement                   $ 5,000,000        
Payment of direct placement fees                     700,000      
Placement agent fees                     $ 650,000      
Warrant term   5 years                 5 years      
JH Darbie & Co Inc [Member] | Oncotelic Warrant [Member]                            
Product Information [Line Items]                            
Warrants to purchase common stock           2,000,000.0                
JH Darbie & Co Inc [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Number of shares issued and sold 100                          
JH Darbie & Co Inc [Member] | Minimum [Member]                            
Product Information [Line Items]                            
Number of shares issued and sold 40                          
PointR [Member]                            
Product Information [Line Items]                            
Net Cash Provided by (Used in) Operating Activities                     $ 4,300,000      
GMP and autotelic BIO [Member]                            
Product Information [Line Items]                            
Service revenue                     0 1,700,000    
Supplemental Agreement [Member] | Golden Mountain Partners LLC [Member]                            
Product Information [Line Items]                            
Payment for services                     1,200,000      
Debt financing                           $ 2,000,000
Subscription Agreements [Member]                            
Product Information [Line Items]                            
Number of shares issued                   100        
Convertible Debt   $ 2,462,299                 $ 2,462,299 $ 1,011,578    
Subscription Agreements [Member] | Edgepoint AI, Inc [Member]                            
Product Information [Line Items]                            
Number of shares issued and sold               100 100          
Number of shares issued               25,000 25,000   25,000      
Stock value, price per share   $ 1.00           $ 1.00 $ 1.00 $ 1.00 $ 1.00      
Stock issued during period           $ 50,000                
Subscription Agreements [Member] | JH Darbie & Co Inc [Member]                            
Product Information [Line Items]                            
Proceeds from Issuance of Common Stock                   $ 5,000,000        
Equity Purchase Agreement [Member]                            
Product Information [Line Items]                            
Stock issued during period             $ 3,400,000              
Proceeds from Issuance of Common Stock             420,000              
Proceeds from Issuance of Private Placement                     $ 400,000      
Equity Purchase Agreement [Member] | Peak One Opportunity Fund, L.P [Member]                            
Product Information [Line Items]                            
Stock issued during period             $ 10,000,000.0              
Common Stock, Par or Stated Value Per Share             $ 0.01              
Geneva Agreement [Member]                            
Product Information [Line Items]                            
Convertible Debt           103,750 $ 203,750              
Proceeds from Issuance of Private Placement                     300,000      
Geneva Agreement [Member] | Maximum [Member]                            
Product Information [Line Items]                            
Convertible Debt           $ 1,200,000                
Note Purchase Agreements [Member] | Autotelic Inc [Member]                            
Product Information [Line Items]                            
Debt instrument, convertible, conversion price         $ 0.18                  
Common Stock, Par or Stated Value Per Share         $ 0.01                  
Debt Instrument, Face Amount         $ 698,500                  
Debt instrument, interest rate, stated percentage         5.00%                  
Debt Instrument, Maturity Date, Description         The Company may prepay the Notes at any time. Events of Default under the Notes include, without limitation, (i) failure to make payments under the Notes within thirty (30) days of the Maturity Date, (ii) breaches of the Note Purchase Agreement or Notes by the Company which is not cured within thirty (30) days of notice of the breach, (iii) bankruptcy, or (iv) a change in control of the Company (as defined in the Note Purchase Agreements). The Majority Holders have the right, at any time not more than five days following the Maturity Date, to elect to convert all, and not less than all, of the outstanding accrued and unpaid interest and principal on the Notes                  
Unsecured Convertible Note Purchase Agreement [Member]                            
Product Information [Line Items]                            
Debt Instrument, Face Amount       $ 1,500,000                    
Debt instrument, interest rate, stated percentage       2.00%                    
Unsecured Covertible Note Purchase Agreement [Member]                            
Product Information [Line Items]                            
Convertible Debt                         $ 500,000  
Debt instrument, interest rate, stated percentage                         2.00%  
License Agreement [Member]                            
Product Information [Line Items]                            
Milestone payment       $ 50,000,000                    
Royalties percent       15.00%                    
Since Inception Date [Member]                            
Product Information [Line Items]                            
Net Income (Loss) Attributable to Parent                     31,000,000.0      
Point R merger agreement [Member]                            
Product Information [Line Items]                            
Working capital deficit   $ 1,300,000                 1,300,000      
Note agreement [Member]                            
Product Information [Line Items]                            
Proceeds from Issuance of Private Placement                     $ 2,000,000