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Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Candidate
Dec. 31, 2014
Mar. 31, 2014
Dec. 31, 2013
Organization, Consolidation and Presentation of Financial Statements [Abstract]        
Number of VDA drug candidates tested 2oxgn_NumberOfDrugCandidates      
Accumulated earnings (deficit) $ (253,927)us-gaap_RetainedEarningsAccumulatedDeficit $ (251,155)us-gaap_RetainedEarningsAccumulatedDeficit    
Cash $ 35,735us-gaap_Cash $ 30,031us-gaap_Cash $ 24,735us-gaap_Cash $ 7,005us-gaap_Cash