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Stockholders' Equity - Common and Preferred Shares - Additional Information (Detail) (USD $)
0 Months Ended 12 Months Ended 3 Months Ended
May 28, 2014
Feb. 18, 2014
Sep. 23, 2013
Apr. 16, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Jun. 30, 2013
Sep. 30, 2013
Nov. 30, 2011
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock authorized         70,000,000us-gaap_CommonStockSharesAuthorized 70,000,000us-gaap_CommonStockSharesAuthorized        
Net proceeds from issuance of common stock and warrants $ 14,822,000oxgn_ProceedsFromIssuanceOfCommonStockAndWarrants $ 10,860,000oxgn_ProceedsFromIssuanceOfCommonStockAndWarrants                
Gross proceeds from issuance of common stock and warrants 16,000,000oxgn_ProceedsFromIssuanceOfCommonStockAndWarrantsInOfferingGross 12,000,000oxgn_ProceedsFromIssuanceOfCommonStockAndWarrantsInOfferingGross                
Exercise of warrants, shares of Company's common stock converted         1,054,625us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights          
Term of warrants 5 years 3 months 18 days 5 years                
Exercise Price $ 2.90us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1 $ 2.75us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1     $ 2.24us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1          
Percentage of warrants owned 4.99%oxgn_ThresholdLimitPercentageOnWarrantsOwned 9.99%oxgn_ThresholdLimitPercentageOnWarrantsOwned                
Increase in percentage of warrants owned 9.99%oxgn_IncreaseInThresholdLimitPercentageOnWarrantsOwned                  
Number of warrant exercised         1,054,625oxgn_ClassOfWarrantOrRightNumberOfWarrantsExercised          
Proceeds from warrant exercises         9,512,000us-gaap_ProceedsFromWarrantExercises 864,000us-gaap_ProceedsFromWarrantExercises        
Gross proceeds     5,800,000us-gaap_ProceedsFromIssuanceInitialPublicOffering 5,000,000us-gaap_ProceedsFromIssuanceInitialPublicOffering            
Net proceeds     4,905,000oxgn_ProceedsFromIssuanceInitialPublicOfferingNet 4,192,000oxgn_ProceedsFromIssuanceInitialPublicOfferingNet            
Number of common stock issued upon conversion       1,377,412us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion            
Number of preferred stock outstanding         0us-gaap_PreferredStockSharesOutstanding 0us-gaap_PreferredStockSharesOutstanding        
Exercisable period of warrants         5 years          
Purchase of common stock at closing         147,145oxgn_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsRelatedParty          
Non-cash deemed dividend to preferred stock           4,799,000us-gaap_PreferredStockDividendsIncomeStatementImpact        
Proceeds from issuance of common stock, net of issuance costs         25,682,000us-gaap_ProceedsFromIssuanceOfCommonStock 1,936,000us-gaap_ProceedsFromIssuanceOfCommonStock 3,317,000us-gaap_ProceedsFromIssuanceOfCommonStock      
Issuance of common stock         20,705,000us-gaap_CommonStockSharesIssued 5,586,000us-gaap_CommonStockSharesIssued        
Weighted average period for recognizing unrecognized compensation cost as expense         2 years 8 months 5 days          
Unrecognized compensation cost related to stock option awards         515,000us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions          
Dividend yield         0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate 0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate 0.00%us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate      
Expense related to stock awards         414,000us-gaap_AllocatedShareBasedCompensationExpense 679,000us-gaap_AllocatedShareBasedCompensationExpense 511,000us-gaap_AllocatedShareBasedCompensationExpense      
Percentage of common stock at closing price         85.00%us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent          
Common stock issued under the 2009 ESPP         10,417us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans          
Officer [Member] | Restricted Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Number of restricted stock granted during period           72,933us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
/ us-gaap_TitleOfIndividualAxis
= us-gaap_OfficerMember
       
Restricted stock granted during period value           199,913us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardGross
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
/ us-gaap_TitleOfIndividualAxis
= us-gaap_OfficerMember
       
2005 Plan [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Maximum number of shares acquired for the award of options, restricted stock and stock appreciation         833,333us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
         
Maximum number of shares granted to any one participant in any fiscal year         200,000oxgn_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumNumberOfSharesThatCanBeGrantedPerEmployee
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
         
Number of participant         1oxgn_NumberOfParticipants
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
         
2005 Plan [Member] | Restricted Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Expense related to stock awards         20,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
259,913us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
0us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_AwardTypeAxis
= us-gaap_RestrictedStockMember
/ us-gaap_PlanNameAxis
= oxgn_TwoThousandAndFivePlanMember
     
Placement Agent and Related Persons [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise Price         $ 2.80us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_RelatedPartyTransactionsByRelatedPartyAxis
= oxgn_PlacementAgentAndRelatedPersonsMember
         
Series A Preferred Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period       5,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
           
Net proceeds     2,103,000oxgn_ProceedsFromIssuanceInitialPublicOfferingNet
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
             
Number of preferred stock outstanding     2,802us-gaap_PreferredStockSharesOutstanding
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
    0us-gaap_PreferredStockSharesOutstanding
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
    2,802us-gaap_PreferredStockSharesOutstanding
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
 
Redeemable value of outstanding balance     2,802,000us-gaap_PreferredStockRedemptionAmount
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
          2,802,000us-gaap_PreferredStockRedemptionAmount
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
 
Non-cash deemed dividend to preferred stock               2,480,000us-gaap_PreferredStockDividendsIncomeStatementImpact
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
   
Series B Preferred Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period     5,800us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesBPreferredStockMember
             
Non-cash deemed dividend to preferred stock                 2,310,000us-gaap_PreferredStockDividendsIncomeStatementImpact
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesBPreferredStockMember
 
Private Placement Series A Warrants [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise of warrants, shares of Company's common stock converted       1,377,412us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesAWarrantsMember
           
Exercise Price       $ 3.40us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesAWarrantsMember
$ 3.4000us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesAWarrantsMember
         
Exercisable period of warrants       5 years            
Purchase of common stock at closing       82,645oxgn_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsRelatedParty
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesAWarrantsMember
           
Private Placement Series B Warrants [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise of warrants, shares of Company's common stock converted       1,377,412us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
           
Exercise Price       $ 3.40us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
$ 3.4000us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
         
Proceeds from warrant exercises         1,118,000us-gaap_ProceedsFromWarrantExercises
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
864,000us-gaap_ProceedsFromWarrantExercises
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
       
Exercisable period of warrants       2 years            
Warrant exercised         350,000oxgn_ClassOfWarrantOrRightExercised
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
270,390oxgn_ClassOfWarrantOrRightExercised
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
       
Public Offering [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Share price of common stock and warrants issued   $ 2.05us-gaap_SharePrice
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
               
Number of warrants issued for each unit issued   0.5us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
               
Common stock issued during period   5,853,657us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
               
Exercise of warrants, shares of Company's common stock converted   2,926,829us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
               
Proceeds from warrant exercises         2,901,000us-gaap_ProceedsFromWarrantExercises
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
         
Common Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period             294,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
     
Exercise of warrants, shares of Company's common stock converted         2,452,431us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
         
Proceeds from warrant exercises         5,493,000us-gaap_ProceedsFromWarrantExercises
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
         
Number of common stock issued upon conversion     2,452,431us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
             
Expense related to stock awards           1,000us-gaap_AllocatedShareBasedCompensationExpense
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Common Stock [Member] | Private Placement Series B Warrants [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period         350,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
270,390us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_ClassOfWarrantOrRightAxis
= oxgn_PrivatePlacementSeriesBWarrantsMember
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Registered Offering [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Share price of common stock and warrants issued $ 2.9625us-gaap_SharePrice
/ us-gaap_StatementEquityComponentsAxis
= oxgn_RegisteredOfferingMember
                 
Number of warrants issued for each unit issued 0.5us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight
/ us-gaap_StatementEquityComponentsAxis
= oxgn_RegisteredOfferingMember
                 
Common stock issued during period 5,400,847us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementEquityComponentsAxis
= oxgn_RegisteredOfferingMember
                 
Exercise of warrants, shares of Company's common stock converted 2,700,424us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementEquityComponentsAxis
= oxgn_RegisteredOfferingMember
                 
Private Placement [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise of warrants, shares of Company's common stock converted         0us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
         
Exercise Price $ 3.7031us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
$ 2.56us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
               
Number of warrant exercised         2,452,431oxgn_ClassOfWarrantOrRightNumberOfWarrantsExercised
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
         
Private Placement [Member] | Series A Preferred Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Number of preferred stock converted           2,198us-gaap_ConversionOfStockSharesConverted1
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
       
Private Placement [Member] | Series B Preferred Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Number of common stock issued upon conversion           2,452,431us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesBPreferredStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
       
Number of preferred stock converted           5,800us-gaap_ConversionOfStockSharesConverted1
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesBPreferredStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
       
Number of preferred stock outstanding         0us-gaap_PreferredStockSharesOutstanding
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesBPreferredStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
         
Private Placement [Member] | Public Offering [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise of warrants, shares of Company's common stock converted   292,682us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementEquityComponentsAxis
= oxgn_PublicOfferingMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
               
Private Placement [Member] | Common Stock [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Number of common stock issued upon conversion           605,422us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
       
Private Placement [Member] | Registered Offering [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Exercise of warrants, shares of Company's common stock converted 216,033us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
/ us-gaap_StatementEquityComponentsAxis
= oxgn_RegisteredOfferingMember
/ us-gaap_SubsidiarySaleOfStockAxis
= us-gaap_PrivatePlacementMember
                 
MLV & Co. LLC [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period         0us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_MlvAndCoLlcMember
422,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_MlvAndCoLlcMember
178,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_MlvAndCoLlcMember
     
Proceeds from issuance of common stock, net of issuance costs           1,936,000us-gaap_ProceedsFromIssuanceOfCommonStock
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_MlvAndCoLlcMember
1,270,000us-gaap_ProceedsFromIssuanceOfCommonStock
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_MlvAndCoLlcMember
     
Lincoln Park Capital Fund, LLC [Member]                    
Stockholders' Equity - Common and Preferred Shares [Line Items]                    
Common stock issued during period             294,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
     
Proceeds from issuance of common stock, net of issuance costs             2,047,000us-gaap_ProceedsFromIssuanceOfCommonStock
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
     
Value of purchase agreement for the sale with Lincoln Park Capital Fund, LLC                   $ 20,000,000oxgn_ValueOfPurchaseAgreementForSale
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
Purchase agreement date of expiration         January 11, 2015          
Minimum purchase price per share                   $ 6.00oxgn_MinimumPurchasePricePerShare
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
Shares issued as a commitment fee             6,493us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
     
Issuance of common stock         0us-gaap_CommonStockSharesIssued
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember
0us-gaap_CommonStockSharesIssued
/ us-gaap_SubsidiarySaleOfStockAxis
= oxgn_LincolnParkCapitalFundMember